Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1752117 | 0.87 | ALDH1A1 (0.48) | HDAC1HDAC2ALDH1A1PKMTP53 | |
| Hydrogen Sulfide SCHEMBL20305480 | 0.86 | ALDH1A1 (0.47) | HDAC1HDAC2ALDH1A1PKMTP53 | |
| SCHEMBL3490799 | 0.81 | ALDH1A1 (0.46) | HDAC1HDAC2ALDH1A1PKM | |
| SCHEMBL10340280 | 0.80 | HDAC1 (0.47) | HDAC1HDAC2ALDH1A1PKM | |
| SCHEMBL28957076 | 0.79 | LMNA (0.52) | LMNAALDH1A1PKMSMN1; SMN2RAB9A | |
| SCHEMBL44725 | 0.78 | ALDH1A1 (0.50) | HDAC1HDAC2LMNAALDH1A1PKM | |
| SCHEMBL9926762 | 0.77 | HDAC1 (0.39) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28279888 | 0.77 | ALDH1A1 (0.40) | LMNAALDH1A1PKMSMN1; SMN2RAB9A | |
| SCHEMBL3183299 | 0.77 | ALDH1A1 (0.40) | HDAC1HDAC2LMNAALDH1A1PKM | |
| SCHEMBL4348222 | 0.77 | HDAC1 (0.39) | HDAC1HDAC2LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107335061-B | Cytotoxic benzodiazepine derivatives | 伊缪诺金公司 | 2021-09-07 | — | — | CN | disclosed |