SCHEMBL10340343

SCHEMBL10340343

O=C(CCSSc1ccccn1)ON1C(=O)C=CC1=O

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
LMNA P02545 1/20 0.41
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
EHMT2 Q96KQ7 1/20 0.39
EHMT1 Q9H9B1 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HPGD P15428 2/20 0.37
HDAC1 Q13547 4/20 0.36
HDAC2 Q92769 4/20 0.36
MEN1 O00255 1/20 0.34
PKM P14618 1/20 0.34
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10340185 0.93 ALDH1A1 (0.40) ALDH1A1LMNAKMT2AMAPTEHMT2
SCHEMBL10340287 0.92 HDAC1 (0.41) ALDH1A1LMNAKMT2AMAPTEHMT2
SCHEMBL10340513 0.91 HDAC1 (0.42) ALDH1A1LMNAKMT2AMAPTEHMT2
SCHEMBL28707482 0.87 ALDH1A1 (0.57) ALDH1A1LMNAKMT2AMAPTRAB9A
SCHEMBL29430092 0.87 ALDH1A1 (0.36) ALDH1A1LMNAKMT2AMAPTEHMT2
SCHEMBL42368 0.86 ALDH1A1 (0.44) ALDH1A1LMNAKMT2AMAPTEHMT2
SCHEMBL29352062 0.86 ALDH1A1 (0.44) ALDH1A1LMNAKMT2AMAPTEHMT2
SCHEMBL13252991 0.83 ALDH1A1 (0.43) ALDH1A1LMNAKMT2AMAPTEHMT2
SCHEMBL18562069 0.82 ALDH1A1 (0.40) ALDH1A1LMNAKMT2AMAPTEHMT2
SCHEMBL12533282 0.82 ALDH1A1 (0.40) ALDH1A1LMNAKMT2AMAPTEHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113039191-B Nucleotide analogues 奇异基因组学系统公司 2024-07-16 CN disclosed
US-11634497-B2 Anti-CCR7 antibody drug conjugates NOVARTIS AG (CH) 2023-04-25 US disclosed
US-20200216548-A1 ANTI-CCR7 ANTIBODY DRUG CONJUGATES NOVARTIS INSTITUTE FOR FUNCTIONAL GENOMICS, INC. DBA THE GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION 2020-07-09 US disclosed
US-8084247-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2011-12-27 US disclosed
US-8084247-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2011-12-27 US disclosed
US-8039251-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2011-10-18 US disclosed
US-8039251-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2011-10-18 US disclosed
US-7960169-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2011-06-14 US disclosed
US-7960169-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2011-06-14 US disclosed
US-7741107-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2010-06-22 US disclosed
US-20100143930-A1 Biological indicator AMERICAN STERILIZER COMPANY (US) 2010-06-10 US disclosed
US-20100143930-A1 Biological indicator AMERICAN STERILIZER COMPANY (US) 2010-06-10 US disclosed
US-7416883-B2 Biological indicator STERIS INC. (US) 2008-08-26 US disclosed
US-7416883-B2 Biological indicator STERIS INC. (US) 2008-08-26 US disclosed
US-20080199903-A1 Biological indicator STERIS INC. (US) 2008-08-21 US disclosed
US-20080199903-A1 Biological indicator STERIS INC. (US) 2008-08-21 US disclosed
EP-0196007-B1 DESMOSINE DERIVATIVES AND REAGENT FOR PREPARING ARTIFICIAL ANTIGENS JAPAN TOBACCO INC. (JP) 1990-01-10 EP disclosed
US-4841055-A Desmosine derivatives and reagent for preparing artificial antigens JAPAN TOBACCO INC. (JP) 1989-06-20 US disclosed
US-4723012-A Desmosine derivatives having a disulfide bond and preparation of artificial antigen using the same JAPAN TOBACCO INC. (JP) 1988-02-02 US disclosed
EP-0196007-A2 Desmosine derivatives and reagent for preparing artificial antigens JAPAN TOBACCO INC. (JP) 1986-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216548-A1 ANTI-CCR7 ANTIBODY DRUG CONJUGATES CCR7, CXCR3, CXCR4 ALDH1A1 2197/4885LMNA 2182/4885KMT2A 2497/4885
US-11634497-B2 Anti-CCR7 antibody drug conjugates CCR7, CXCR3, CXCR4 ALDH1A1 2197/4885LMNA 2182/4885KMT2A 2497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.