Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | TK1 | P04183 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | TK2 | O00142 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340153 | 0.86 | ADRB1 (0.53) | ADRB1DNMT1TK1LMNASMN1; SMN2 | |
| SCHEMBL10340307 | 0.86 | ADRB1 (0.53) | ADRB1DNMT1TK1LMNASMN1; SMN2 | |
| SCHEMBL10438093 | 0.82 | ADRB1 (0.56) | ADRB1DNMT1TK1LMNASMN1; SMN2 | |
| SCHEMBL9633791 | 0.82 | ADRB1 (0.56) | ADRB1DNMT1TK1LMNASMN1; SMN2 | |
| SCHEMBL10422310 | 0.82 | ADRB1 (0.56) | ADRB1DNMT1TK1LMNASMN1; SMN2 | |
| SCHEMBL10420598 | 0.80 | LMNA (0.56) | ADRB1DNMT1TK1LMNASMN1; SMN2 | |
| Ropidoxuridine SCHEMBL20456175 | 0.80 | TK1 (0.56) | ADRB1DNMT1TK1LMNASMN1; SMN2 | |
| SCHEMBL10340155 | 0.80 | ADRB1 (0.56) | ADRB1DNMT1TK1LMNASMN1; SMN2 | |
| Ropidoxuridine SCHEMBL8602575 | 0.80 | TK1 (0.56) | ADRB1DNMT1TK1LMNASMN1; SMN2 | |
| Ropidoxuridine SCHEMBL9150120 | 0.80 | TK1 (0.56) | ADRB1DNMT1TK1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175004-B1 | NOVEL 5-SUBSTITUTED 2-PYRIMIDINONE NUCLEOSIDES AND METHODS OF USE | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-01-03 | — | — | EP | claimed |
| US-4782142-A | VIRICIDES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1988-11-01 | — | — | US | claimed |
| EP-0175004-A2 | Novel 5-substituted 2-pyrimidinone nucleosides and methods of use | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1986-03-26 | — | — | EP | claimed |
| US-4895937-A | VIRICIDES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0175004-B1 | NOVEL 5-SUBSTITUTED 2-PYRIMIDINONE NUCLEOSIDES AND METHODS OF USE | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4782142-A | VIRICIDES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0175004-A2 | Novel 5-substituted 2-pyrimidinone nucleosides and methods of use | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1986-03-26 | — | — | EP | disclosed |