Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 8/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.43 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.43 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807362 | 0.81 | CXCL8 (0.62) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL13254960 | 0.78 | CXCL8 (0.61) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL4906312 | 0.78 | CXCL8 (0.61) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL1034051 | 0.75 | CXCL8 (0.67) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL4906690 | 0.74 | CXCL8 (0.58) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL13186033 | 0.72 | CXCL8 (0.68) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL5974909 | 0.71 | CXCL8 (0.59) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL6931840 | 0.70 | CXCL8 (0.69) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL7716835 | 0.69 | CXCL8 (0.73) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL11403823 | 0.69 | CXCL8 (0.73) | CXCL8PTGS2TTRPTGS1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140057959-A1 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | UNIVERSIDADE ESTADUAL PAULISTA JULIO DE MESQUITA FILHO - UNESP (BR) | 2014-02-27 | — | — | US | claimed |
| EP-2276729-A2 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S. A. (BR) | 2011-01-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140057959-A1 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | TPMT, UTS2R, NSUN3 | CXCL8 11/4885PTGS2 217/4885TTR 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.