Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.31 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109627 | 0.92 | LMNA (0.37) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL20384698 | 0.92 | LMNA (0.37) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL29398201 | 0.92 | LMNA (0.37) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30767122 | 0.91 | LMNA (0.36) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL10340283 | 0.89 | LMNA (0.37) | LMNAHDAC1HDAC2SMN1; SMN2HPGD | |
| SCHEMBL17072479 | 0.86 | LMNA (0.33) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL17070328 | 0.86 | SMN1; SMN2 (0.33) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL26199584 | 0.86 | LMNA (0.32) | LMNA | |
| SCHEMBL15752290 | 0.85 | LMNA (0.33) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL321113 | 0.85 | LMNA (0.38) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196007-B1 | DESMOSINE DERIVATIVES AND REAGENT FOR PREPARING ARTIFICIAL ANTIGENS | JAPAN TOBACCO INC. (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4841055-A | Desmosine derivatives and reagent for preparing artificial antigens | JAPAN TOBACCO INC. (JP) | 1989-06-20 | — | — | US | disclosed |
| US-4723012-A | Desmosine derivatives having a disulfide bond and preparation of artificial antigen using the same | JAPAN TOBACCO INC. (JP) | 1988-02-02 | — | — | US | disclosed |
| EP-0196007-A2 | Desmosine derivatives and reagent for preparing artificial antigens | JAPAN TOBACCO INC. (JP) | 1986-10-01 | — | — | EP | disclosed |