Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398201 | 1.00 | LMNA (0.37) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL109627 | 1.00 | LMNA (0.37) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30767122 | 0.99 | LMNA (0.36) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL10340552 | 0.92 | LMNA (0.34) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL17072479 | 0.90 | LMNA (0.33) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL15752290 | 0.89 | LMNA (0.33) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL29351145 | 0.89 | LMNA (0.38) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL321113 | 0.89 | LMNA (0.38) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL159766 | 0.89 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 | |
| SCHEMBL8610607 | 0.89 | LMNA (0.38) | LMNASMN1; SMN2HPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11571480-B2 | Multi-ligand drug conjugates and uses thereof | Coherent Biopharma I, Limited (HK) | 2023-02-07 | — | — | US | disclosed |
| US-20180200377-A1 | MULTI-LIGAND DRUG CONJUGATES AND USES THEREOF | Coherent Biopharma I, Limited (HK) | 2018-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11571480-B2 | Multi-ligand drug conjugates and uses thereof | CD44, CD47, SELPLG | LMNA 3580/4885SMN1; SMN2 2081/4885HPGD 3923/4885 |
| US-20180200377-A1 | MULTI-LIGAND DRUG CONJUGATES AND USES THEREOF | CD44, CD47, SELPLG | LMNA 3580/4885SMN1; SMN2 2081/4885HPGD 3923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.