SCHEMBL29398201

SCHEMBL29398201

CC(CCC(=O)ON1C(=O)CCC1=O)SSc1ccccn1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.37
SMN1; SMN2 Q16637 5/20 0.36
HPGD P15428 4/20 0.36
HSD17B10 Q99714 1/20 0.36
ALDH1A1 P00352 6/20 0.34
EHMT2 Q96KQ7 1/20 0.34
EHMT1 Q9H9B1 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
TSHR P16473 1/20 0.34
RAB9A P51151 3/20 0.33
NPC1 O15118 2/20 0.33
MAPT P10636 4/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PKM P14618 1/20 0.33
PSMB8 P28062 1/20 0.33
PSMB5 P28074 1/20 0.33
MAPK10 P53779 1/20 0.32
RGS12 O14924 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20384698 1.00 LMNA (0.37) LMNASMN1; SMN2HPGDHSD17B10ALDH1A1
SCHEMBL109627 1.00 LMNA (0.37) LMNASMN1; SMN2HPGDHSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL30767122 0.99 LMNA (0.36) LMNASMN1; SMN2HPGDHSD17B10ALDH1A1
SCHEMBL10340552 0.92 LMNA (0.34) LMNASMN1; SMN2HPGDHSD17B10ALDH1A1
SCHEMBL17072479 0.90 LMNA (0.33) LMNASMN1; SMN2HPGDHSD17B10ALDH1A1
SCHEMBL15752290 0.89 LMNA (0.33) LMNASMN1; SMN2HPGDHSD17B10ALDH1A1
SCHEMBL29351145 0.89 LMNA (0.38) LMNASMN1; SMN2HPGDHSD17B10ALDH1A1
SCHEMBL321113 0.89 LMNA (0.38) LMNASMN1; SMN2HPGDHSD17B10ALDH1A1
SCHEMBL159766 0.89 SMN1; SMN2 (0.39) LMNASMN1; SMN2HPGDHSD17B10ALDH1A1
SCHEMBL8610607 0.89 LMNA (0.38) LMNASMN1; SMN2HPGDHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151464-A1 ALPHA-PARTICLE RADIONUCLIDE-ANTIBODY CONJUGATES FOR TREATMENT OF SOLID TUMORS THE JOHNS HOPKINS UNIVERSITY (US) 2025-07-17 WO claimed
EP-4347661-A1 TREATMENT OF CANCER IN PATIENTS WITH SOLUBLE FR-ALPHA ImmunoGen, Inc. (US) 2024-04-10 EP claimed
WO-2022256507-A1 TREATMENT OF CANCER IN PATIENTS WITH SOLUBLE FR-ALPHA IMMUNOGEN, INC. (US) 2022-12-08 WO claimed
EP-4746899-A1 TREATMENT OF CANCER PATIENTS WITH TUMOR INFILTRATING LYMPHOCYTE THERAPIES IN COMBINATION WITH TROP-2 TARGETING ADC Iovance Biotherapeutics, Inc. (US) 2026-05-27 EP disclosed
EP-4642491-A1 METHOD FOR GLYCOPROTEIN MODIFICATION Honeybear Biosciences Inc. (TW) 2025-11-05 EP disclosed
EP-4642488-A1 ANTIBODY DRUG CONJUGATES Yale University (US) 2025-11-05 EP disclosed
US-20250255975-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP Bicyclerd Limited (GB) 2025-08-14 US disclosed
EP-4547284-A1 ANTI-ROR1 ANTIBODIES AND ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-ROR1 ANTIBODIES OR ANTIBODY CONJUGATES, AND METHODS OF MAKING AND USING ANTI-ROR1 ANTIBODIES AND ANTIBODY CONJUGATES Sutro Biopharma, Inc. (US) 2025-05-07 EP disclosed
EP-4531927-A1 DOSAGE REGIMEN OF AN ANTI-CDH6 ANTIBODY-DRUG CONJUGATE Daiichi Sankyo Company, Limited (JP) 2025-04-09 EP disclosed
WO-2025048683-A1 METHOD FOR DETECTION AND QUANTIFICATION OF CELL FREE DNA IN BIOLOGICAL SAMPLE SANTERSUS AG (CH) 2025-03-06 WO disclosed
EP-4514857-A2 ANTI-NUCLEOPHOSMIN 1 ANTIBODY AND ANTIBODY CONJUGATE COMBINATION THERAPIES The Children's Medical Center Corporation (US) 2025-03-05 EP disclosed
WO-2022136555-A1 IMPROVED CD30 TARGETING ANTIBODY DRUG CONJUGATES AND USES THEREOF LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) 2022-06-30 WO disclosed
EP-4017532-A1 INTERCELLULAR ADHESION MOLECULE 1 (ICAM1) ANTIBODY DRUG CONJUGATE AND USES THEREOF Children's Medical Center Corporation (US) 2022-06-29 EP disclosed
WO-2022103983-A9 FLUORENYLMETHYLOXYCARBONYL AND FLUORENYLMETHYLAMINOCARBONYL COMPOUNDS, PROTEIN CONJUGATES THEREOF, AND METHODS FOR THEIR USE SUTRO BIOPHARMA, INC. (US) 2022-06-09 WO disclosed
WO-2022112942-A2 ANTI-CD48 ANTIBODIES, ANTIBODY DRUG CONJUGATES, AND USES THEREOF NOVARTIS AG (CH) 2022-06-02 WO disclosed
WO-2022103983-A2 FLUORENYLMETHYLOXYCARBONYL AND FLUORENYLMETHYLAMINOCARBONYL COMPOUNDS, PROTEIN CONJUGATES THEREOF, AND METHODS FOR THEIR USE SUTRO BIOPHARMA, INC. (US) 2022-05-19 WO disclosed
EP-3986468-A1 ANTIB0DY-ALK5 INHIBITOR CONJUGATES AND THEIR USES Synthis Therapeutics, Inc. (US) 2022-04-27 EP disclosed
EP-3980423-A1 5H-PYRROLO[3,2-D]PYRIMIDINE-2,4-DIAMINO COMPOUNDS AND ANTIBODY CONJUGATES THEREOF Sutro Biopharma, Inc. (US) 2022-04-13 EP disclosed
EP-3980080-A1 IMMUNOMODULATOR ANTIBODY DRUG CONJUGATES AND USES THEREOF Sutro Biopharma, Inc. (US) 2022-04-13 EP disclosed
EP-3962951-A1 ANTI-BCMA ANTIBODY CONJUGATES Sutro Biopharma, Inc. (US) 2022-03-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250255975-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR MT1-MMP MMEL1, MMP3, TIMP3 LMNA 1332/4885SMN1; SMN2 2304/4885HPGD 1617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.