Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | CCR2 | P41597 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340425 | 0.94 | SIGMAR1 (0.48) | SIGMAR1CHRM1MAOAMAOBDRD4 | |
| Hydrochloric Acid SCHEMBL10338967 | 0.90 | SIGMAR1 (0.57) | SIGMAR1CHRM1MAOAMAOBDRD4 | |
| SCHEMBL10340659 | 0.88 | DRD4 (0.57) | IGF1RALOX15SIGMAR1CHRM1MAOA | |
| SCHEMBL10340421 | 0.86 | SIGMAR1 (0.58) | IGF1RALOX15SIGMAR1CHRM1MAOA | |
| SCHEMBL10340427 | 0.86 | L3MBTL1 (0.60) | SIGMAR1MAOAMAOBLMNAL3MBTL1 | |
| SCHEMBL10340306 | 0.84 | SIGMAR1 (0.67) | SIGMAR1CHRM1MAOAMAOBDRD4 | |
| SCHEMBL10340415 | 0.82 | SIGMAR1 (0.67) | SIGMAR1DRD4CXCR3 | |
| SCHEMBL10340664 | 0.81 | SIGMAR1 (0.67) | SIGMAR1MAOAMAOB | |
| SCHEMBL3586870 | 0.80 | SIGMAR1 (0.55) | SIGMAR1DRD4HRH3LMNATEAD1 | |
| SCHEMBL10340309 | 0.78 | CCR5 (0.52) | SIGMAR1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354568-A2 | Novel catechol derivatives | Japan Tobacco Inc. (JP) | 1990-02-14 | — | — | EP | claimed |
| EP-0354568-A2 | Novel catechol derivatives | Japan Tobacco Inc. (JP) | 1990-02-14 | — | — | EP | disclosed |