SCHEMBL10340704

SCHEMBL10340704

O=C(COc1ccc(Cl)c(Cl)c1)ON=C(c1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.59
SMN1; SMN2 Q16637 3/20 0.56
MAPT P10636 5/20 0.53
ALDH1A1 P00352 2/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
HTT P42858 1/20 0.51
GLA P06280 1/20 0.50
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.48
TDP1 Q9NUW8 4/20 0.47
MRGPRX4 Q96LA9 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10340675 0.90 L3MBTL1 (0.71) L3MBTL1SMN1; SMN2MAPTALDH1A1MEN1
SCHEMBL10340699 0.89 L3MBTL1 (0.69) L3MBTL1SMN1; SMN2MAPTALDH1A1MEN1
SCHEMBL10795434 0.77 L3MBTL1 (0.49) L3MBTL1SMN1; SMN2MAPTALDH1A1MEN1
SCHEMBL10340695 0.77 L3MBTL1 (0.52) L3MBTL1SMN1; SMN2MAPTALDH1A1MEN1
SCHEMBL10340733 0.76 L3MBTL1 (0.66) L3MBTL1SMN1; SMN2MAPTALDH1A1MEN1
SCHEMBL9368173 0.75 MRGPRX4 (0.57) SMN1; SMN2MAPTALDH1A1MEN1KMT2A
SCHEMBL10795441 0.73 L3MBTL1 (0.46) L3MBTL1SMN1; SMN2MAPTALDH1A1MEN1
SCHEMBL10795801 0.72 L3MBTL1 (0.57) L3MBTL1SMN1; SMN2MAPTALDH1A1MEN1
SCHEMBL10824088 0.72 L3MBTL1 (0.47) L3MBTL1SMN1; SMN2MAPTALDH1A1MEN1
SCHEMBL10907809 0.72 RAB9A (0.62) L3MBTL1SMN1; SMN2MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0170906-B1 PLANT-PROTECTING AGENTS BASED ON OXIME ESTERS HOECHST AKTIENGESELLSCHAFT (DE) 1990-03-07 EP disclosed