SCHEMBL10907809

SCHEMBL10907809

O=C(ON=C(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.62
NPC1 O15118 6/20 0.62
SMN1; SMN2 Q16637 5/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
ALDH1A1 P00352 7/20 0.60
KMT2A Q03164 3/20 0.60
POLB P06746 2/20 0.60
MAPT P10636 2/20 0.57
MAPK1 P28482 1/20 0.57
PKM P14618 2/20 0.55
LMNA P02545 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
GAA P10253 1/20 0.52
HPGD P15428 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Diphenylmethylidene)Amino Benzoate SCHEMBL92010 0.89 ALDH1A1 (0.66) RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A
Benzoyl Peroxide SCHEMBL10536706 0.77 LMNA (0.74) RAB9ANPC1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL247591 0.77 CES2 (0.65) RAB9ANPC1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL10340675 0.77 L3MBTL1 (0.71) SMN1; SMN2L3MBTL1ALDH1A1KMT2AMAPT
SCHEMBL10429947 0.77 RAB9A (0.68) RAB9ANPC1SMN1; SMN2L3MBTL1POLB
SCHEMBL11333722 0.76 ALDH1A1 (0.50) RAB9ANPC1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL10340699 0.75 L3MBTL1 (0.69) SMN1; SMN2L3MBTL1ALDH1A1KMT2AMAPT
SCHEMBL12328997 0.74 RAB9A (0.48) RAB9ANPC1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL13431309 0.74 NPC1 (0.53) RAB9ANPC1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL8760132 0.74 L3MBTL1 (0.56) RAB9ANPC1SMN1; SMN2L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4590145-A Photopolymerization initiator comprised of thioxanthones and oxime esters DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1986-05-20 US disclosed