Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340783 | 0.85 | ALDH1A1 (0.38) | ACHENFE2L2ALDH1A1ALOX15CES2 | |
| SCHEMBL17351954 | 0.81 | TSHR (0.32) | — | |
| SCHEMBL7651889 | 0.75 | ACHE (0.35) | ACHENFE2L2CES2CES1TAAR1 | |
| SCHEMBL10795313 | 0.75 | ACHE (0.40) | ACHENFE2L2CES2CES1TAAR1 | |
| SCHEMBL11587240 | 0.75 | CES2 (0.36) | ACHENFE2L2ALDH1A1ALOX15CES2 | |
| SCHEMBL10794254 | 0.73 | ESR1 (0.43) | ACHENFE2L2 | |
| Hydrochloric Acid SCHEMBL10813694 | 0.73 | CES2 (0.34) | ACHENFE2L2ALDH1A1ALOX15CES2 | |
| SCHEMBL10340771 | 0.72 | TSHR (0.45) | ALDH1A1CES2CES1 | |
| SCHEMBL11780374 | 0.70 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL8643451 | 0.70 | TSHR (0.43) | ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170102-B1 | PROCESS FOR PREPARING BIFUNCTIONAL TERTIARY AROMATIC PHOSPHINE SULPHIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-14 | — | — | EP | disclosed |
| EP-0230243-B1 | PROCESS FOR THE PREPARATION OF BIFUNCTIONAL TERTIARY AROMATIC PHOSPHANSULFIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-07 | — | — | EP | disclosed |
| US-4816605-A | Process for the preparation of bifunctional tertiary aromatic phosphine oxides | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-28 | — | — | US | disclosed |
| EP-0230243-A1 | Process for the preparation of bifunctional tertiary aromatic phosphansulfides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-29 | — | — | EP | disclosed |
| US-4670601-A | Process for the preparation of bifunctional tertiary aromatic phosphine sulfides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-06-02 | — | — | US | disclosed |
| EP-0170102-A1 | Process for preparing bifunctional tertiary aromatic phosphine sulphides | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-02-05 | — | — | EP | disclosed |