Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.57 |
| ▸ | RELA | Q04206 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20594544 | 0.98 | FAAH (0.54) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9405912 | 0.98 | FAAH (0.54) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL11227878 | 0.95 | FAAH (0.56) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9475541 | 0.94 | RARB (0.54) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9405799 | 0.94 | RARB (0.54) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9406265 | 0.91 | FAAH (0.51) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL19789523 | 0.91 | RARB (0.50) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9641396 | 0.88 | RARB (0.53) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9640193 | 0.88 | RARB (0.53) | NPC1LMNANFKB1NFKB2RELA | |
| SCHEMBL9405786 | 0.88 | RARB (0.59) | NPC1LMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952337-A | FERROELECTRIC MATERIALS | THE SECRETARY OF STATE FOR DEFENCE IN HER MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM, OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1990-08-28 | — | — | US | disclosed |
| EP-0210215-B1 | FLUORINATED PHENYL ESTERS AND LIQUID CRYSTAL MATERIALS AND DEVICES CONTAINING THEM | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1990-03-14 | — | — | EP | disclosed |
| US-4769176-A | Biphenyl esters and liquid crystal materials and devices containing them | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1988-09-06 | — | — | US | disclosed |
| EP-0210215-A1 | Fluorinated phenyl esters and liquid crystal materials and devices containing them. | SECR DEFENCE BRIT (GB) | 1987-02-04 | — | — | EP | disclosed |
| WO-1986004327-A1 | BIPHENYL ESTERS AND LIQUID CRYSTAL MATERIALS AND DEVICES CONTAINING THEM | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) | 1986-07-31 | — | — | WO | disclosed |