Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475541 | 0.96 | RARB (0.54) | RARBFAAHSMN1; SMN2LMNANPC1 | |
| SCHEMBL9405799 | 0.96 | RARB (0.54) | RARBFAAHSMN1; SMN2LMNANPC1 | |
| SCHEMBL20594544 | 0.93 | FAAH (0.54) | RARBFAAHSMN1; SMN2LMNANPC1 | |
| SCHEMBL9405912 | 0.93 | FAAH (0.54) | RARBFAAHSMN1; SMN2LMNANPC1 | |
| SCHEMBL10340804 | 0.91 | NPC1 (0.57) | FAAHSMN1; SMN2LMNANPC1NFKB1 | |
| SCHEMBL11227878 | 0.91 | FAAH (0.56) | FAAHSMN1; SMN2LMNANPC1NFKB1 | |
| SCHEMBL9641396 | 0.90 | RARB (0.53) | RARBFAAHSMN1; SMN2LMNANPC1 | |
| SCHEMBL9640193 | 0.90 | RARB (0.53) | RARBFAAHSMN1; SMN2LMNANPC1 | |
| SCHEMBL9405786 | 0.89 | RARB (0.59) | RARBFAAHSMN1; SMN2LMNANPC1 | |
| SCHEMBL9641079 | 0.88 | RARB (0.53) | RARBSMN1; SMN2MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |