SCHEMBL9475541

SCHEMBL9475541

CCCCCCCCOc1ccc(-c2ccc(C(=O)Oc3ccc(CCCCC)cc3F)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.54
FAAH O00519 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 2/20 0.50
LMNA P02545 2/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
MAPT P10636 1/20 0.49
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
RARA P10276 1/20 0.47
RARG P13631 1/20 0.47
PLA2G4B P0C869 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9405799 1.00 RARB (0.54) RARBFAAHSMN1; SMN2NPC1LMNA
SCHEMBL20594544 0.97 FAAH (0.54) RARBFAAHSMN1; SMN2NPC1LMNA
SCHEMBL9405912 0.97 FAAH (0.54) RARBFAAHSMN1; SMN2NPC1LMNA
SCHEMBL19789523 0.96 RARB (0.50) RARBFAAHSMN1; SMN2NPC1LMNA
SCHEMBL10340804 0.94 NPC1 (0.57) FAAHSMN1; SMN2NPC1LMNANFKB1
SCHEMBL11227878 0.94 FAAH (0.56) FAAHSMN1; SMN2NPC1LMNANFKB1
SCHEMBL9641396 0.94 RARB (0.53) RARBFAAHSMN1; SMN2NPC1LMNA
SCHEMBL9640193 0.94 RARB (0.53) RARBFAAHSMN1; SMN2NPC1LMNA
SCHEMBL9640217 0.91 RARB (0.53) RARBSMN1; SMN2MAPTRARARARG
SCHEMBL9641079 0.91 RARB (0.53) RARBSMN1; SMN2MAPTRARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158020-B2 Liquid crystal element, optical path deflecting element, and image displaying apparatus RICOH COMPANY, LTD. (JP) 2012-04-17 US disclosed
US-20080204608-A1 Liquid Crystal Element, Optical Path Deflecting Element, and Image Displaying Apparatus RICOH COMPANY, LTD. (JP) 2008-08-28 US disclosed
EP-0391986-B1 DISPLAY ELEMENT BASED ON THE ELECTROCLINIC EFFECT MERCK PATENT GMBH (DE) 1993-12-08 EP disclosed
US-5182047-A FLUORINATED BIPHENYLDIOLE DERIVATIVES MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1993-01-26 US disclosed
EP-0368975-B1 FLUORINATED BIPHENYLDIOLE DERIVATIVES MERCK PATENT GmbH (DE) 1992-12-16 EP disclosed
US-5116527-A Liquid crystal mixture of two chiral components and one non-chiral componene MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1992-05-26 US disclosed
EP-0391986-A1 DISPLAY ELEMENT BASED ON THE ELECTROCLINIC EFFECT. MERCK PATENT GMBH (DE) 1990-10-17 EP disclosed
EP-0210215-B1 FLUORINATED PHENYL ESTERS AND LIQUID CRYSTAL MATERIALS AND DEVICES CONTAINING THEM The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1990-03-14 EP disclosed
EP-0357702-A1 FLUORINATED OLIGOPHENYL DERIVATIVES. MERCK PATENT GMBH (DE) 1990-03-14 EP disclosed
WO-1989011451-A1 DISPLAY ELEMENT BASED ON THE ELECTROCLINIC EFFECT MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-11-30 WO disclosed
WO-1989006678-A1 FLUORINATED OLIGOPHENYL DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-07-27 WO disclosed
EP-0302875-A1 OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM. SECR DEFENCE BRIT (GB) 1989-02-15 EP disclosed
WO-1987006577-A2 OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) 1987-11-05 WO disclosed