Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341108 | 0.89 | ATM (0.44) | ATMNAMPTRAB9ANPC1GAA | |
| SCHEMBL9619720 | 0.88 | ATM (0.42) | ATMNAMPTRAB9ANPC1GAA | |
| SCHEMBL16425212 | 0.86 | ATM (0.42) | ATM | |
| SCHEMBL10340920 | 0.86 | LMNA (0.50) | ATMPOLBLMNA | |
| SCHEMBL23093931 | 0.81 | ATM (0.54) | ATMNAMPTRAB9ANPC1GAA | |
| SCHEMBL29060943 | 0.81 | ATM (0.54) | ATMNAMPTRAB9ANPC1GAA | |
| SCHEMBL10341100 | 0.81 | RAB9A (0.46) | ATMRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL10340942 | 0.81 | KDM4E (0.42) | ATMRAB9ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL10340906 | 0.81 | ATM (0.35) | ATMRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10341075 | 0.80 | ALDH1A1 (0.35) | ATMSMN1; SMN2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61280480-A | — | — | None | — | — | JP | disclosed |
| EP-0199822-B1 | PYRAZOLECARBOXAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND BACTERICIDES CONTAINING THEM AS EFFECTIVE INGREDIENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-4742074-A | Pyrazolecarboxamide derivative and fungicide containing it as active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-05-03 | — | — | US | disclosed |
| JP-S61280480-A | PYRAZOLECARBOXAMIDE COMPOUND AND FUNGICIDE CONTAINING SAID COMPOUND AS ACTIVE COMPONENT | SUMITOMO CHEM CO LTD | 1986-12-11 | — | — | JP | disclosed |
| EP-0199822-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND BACTERICIDES CONTAINING THEM AS EFFECTIVE INGREDIENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-11-05 | — | — | EP | disclosed |