Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | CFD | P00746 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 10/20 | 0.47 |
| ▸ | MAOB | P27338 | 10/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10343101 | 0.87 | F2 (0.49) | F2CFDKIF11ELANEMAOA | |
| SCHEMBL10342820 | 0.87 | MAOA (0.57) | F2CFDKIF11ELANEMAOA | |
| SCHEMBL10343133 | 0.84 | F2 (0.46) | F2CFDMAOAMAOBACHE | |
| SCHEMBL10342828 | 0.83 | F2 (0.47) | F2CFDELANEMAOAMAOB | |
| SCHEMBL2722206 | 0.80 | KDM4E (0.53) | F2CFDMAOAMAOBACHE | |
| SCHEMBL7903542 | 0.79 | NOS1 (0.61) | KIF11DAO | |
| SCHEMBL29442197 | 0.77 | NOS1 (0.62) | F2CFDKIF11ELANEMAOA | |
| SCHEMBL3435898 | 0.77 | NOS1 (0.62) | F2CFDKIF11ELANEMAOA | |
| SCHEMBL19304159 | 0.76 | MAOA (0.42) | F2CFDMAOAMAOBACHE | |
| SCHEMBL9004440 | 0.76 | NOS1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728673-A | BLOWING AGENT OF ISATOIC ANHYDRIDE DERIVATIVE IN PRESCENT OF NEUTRAL SALT | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-01 | — | — | US | claimed |
| EP-0234219-B1 | PROCESS FOR FOANING ESTER AND/OR CARBONATE GROUPS CONTAINING THERMOPLASTIC RESINS | BAYER AG (DE) | 1990-04-18 | — | — | EP | disclosed |
| EP-0135367-B1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1988-03-16 | — | — | EP | disclosed |
| US-4728673-A | BLOWING AGENT OF ISATOIC ANHYDRIDE DERIVATIVE IN PRESCENT OF NEUTRAL SALT | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-01 | — | — | US | disclosed |
| EP-0234219-A2 | Process for foaning ester and/or carbonate groups containing thermoplastic resins | BAYER AG (DE) | 1987-09-02 | — | — | EP | disclosed |
| US-4659718-A | VASODILATION | THE BOOTS COMPANY PLC (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0135367-A1 | Therapeutic agents | The Boots Company PLC (GB) | 1985-03-27 | — | — | EP | disclosed |