SCHEMBL3435898

SCHEMBL3435898

Cc1ccc2c(=O)oc(=O)[nH]c2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.62
NOS3 P29474 1/20 0.62
NOS2 P35228 1/20 0.62
F2 P00734 1/20 0.56
CFD P00746 1/20 0.56
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
KIF11 P52732 3/20 0.47
ALDH1A1 P00352 2/20 0.45
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 1/20 0.45
RXFP1 Q9HBX9 1/20 0.44
ELANE P08246 1/20 0.42
CDK4 P11802 1/20 0.41
CCND1 P24385 1/20 0.41
CAMK2B Q13554 1/20 0.41
CAMK2G Q13555 1/20 0.41
CAMK2D Q13557 1/20 0.41
CAMK2A Q9UQM7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29442197 1.00 NOS1 (0.62) NOS1NOS3NOS2F2CFD
SCHEMBL1202291 0.85 NOS1 (0.62) NOS1NOS3NOS2F2CFD
SCHEMBL29891596 0.85 NOS1 (0.62) NOS1NOS3NOS2F2CFD
SCHEMBL7422358 0.78 F2 (0.56) NOS1NOS3NOS2F2CFD
SCHEMBL12324556 0.78 F2 (0.56) NOS1NOS3NOS2F2CFD
SCHEMBL31607092 0.78 F2 (0.56) F2CFDMAOAMAOBKIF11
SCHEMBL31607095 0.78 F2 (0.56) F2CFDMAOAMAOBKIF11
SCHEMBL1202554 0.78 F2 (0.56) F2CFDMAOAMAOBALDH1A1
SCHEMBL625761 0.78 LMNA (0.62) NOS1NOS3NOS2F2CFD
SCHEMBL30549739 0.78 F2 (0.56) F2CFDMAOAMAOBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118727475-A Room temperature salt-free rapid reactive dyeing and recycling method suitable for cellulose fibers 绍兴劲草化工有限公司 2024-10-01 CN claimed
US-4728673-A BLOWING AGENT OF ISATOIC ANHYDRIDE DERIVATIVE IN PRESCENT OF NEUTRAL SALT BAYER AKTIENGESELLSCHAFT (DE) 1988-03-01 US claimed
EP-4727923-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA University of Georgia Research Foundation, Inc. (US) 2026-04-22 EP disclosed
US-20260098012-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA UNIV GEORGIA (US) 2026-04-09 US disclosed
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP disclosed
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2025-11-25 US disclosed
US-20250235543-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2025-07-24 US disclosed
US-20250171452-A1 TRYPTANTHRIN DERIVATIVES AND USES THEREOF VISCIENT BIO, INC. 2025-05-29 US disclosed
EP-4551208-A1 PHARMACEUTICAL COMPOSITION, METHODS OF USE THEREOF FOR TREATING COCAINE ADDICTION, AND NOVEL USE OF HAUSP K444R POINT MUTANT MOUSE Pharwar Biotechnology, Inc. Pte. Ltd. (SG) 2025-05-14 EP disclosed
US-20250091982-A1 Pharmaceutical Composition, Methods of Use Thereof for Treating Cocaine Addiction, and Novel Use of Hausp K444R Point Mutant Mouse PHARWAR BIOTECHNOLOGY, INC. PTE. LTD. (SG) 2025-03-20 US disclosed
EP-4514804-A1 TRYPTANTHRIN DERIVATIVES AND USES THEREOF Viscient Bio, Inc. (US) 2025-03-05 EP disclosed
US-6884801-B1 Imidazoline derivatives as alpha-1A adrenoceptor ligands SMITHKLINE BEECHAM CORPORATION (US) 2005-04-26 US disclosed
EP-1175406-A1 IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS GLAXO GROUP LIMITED (GB) 2002-01-30 EP disclosed
WO-2000066563-A1 IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS GLAXO GROUP LIMITED (GB) 2000-11-09 WO disclosed
EP-0234219-B1 PROCESS FOR FOANING ESTER AND/OR CARBONATE GROUPS CONTAINING THERMOPLASTIC RESINS BAYER AG (DE) 1990-04-18 EP disclosed
EP-0135367-B1 THERAPEUTIC AGENTS The Boots Company PLC (GB) 1988-03-16 EP disclosed
US-4728673-A BLOWING AGENT OF ISATOIC ANHYDRIDE DERIVATIVE IN PRESCENT OF NEUTRAL SALT BAYER AKTIENGESELLSCHAFT (DE) 1988-03-01 US disclosed
EP-0234219-A2 Process for foaning ester and/or carbonate groups containing thermoplastic resins BAYER AG (DE) 1987-09-02 EP disclosed
US-4659718-A VASODILATION THE BOOTS COMPANY PLC (GB) 1987-04-21 US disclosed
EP-0135367-A1 Therapeutic agents The Boots Company PLC (GB) 1985-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091982-A1 Pharmaceutical Composition, Methods of Use Thereof for Treating Cocaine Addiction, and Novel Use of Hausp K444R Point Mutant Mouse CES2, HDAC6, CHRNB4 NOS1 1749/4885NOS3 2016/4885NOS2 2300/4885
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DGKK, DGKG, DGKA NOS1 2212/4885NOS3 2090/4885NOS2 2079/4885
US-20260098012-A1 TETRAHYDROACRIDINONE ANALOGUES FOR TREATMENT AND PREVENTION OF MALARIA CD47, SLC11A2, G6PD NOS1 793/4885NOS3 537/4885NOS2 890/4885
US-20250171452-A1 TRYPTANTHRIN DERIVATIVES AND USES THEREOF IDO2, IDO1, TPSB2 NOS1 1545/4885NOS3 773/4885NOS2 230/4885
US-20250235543-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, TP53BP1 NOS1 4234/4885NOS3 4735/4885NOS2 4650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.