Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | EDNRA | P25101 | 8/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13677633 | 0.84 | MAPT (0.55) | MAPTKDM4EGAATDP1L3MBTL1 | |
| SCHEMBL10048751 | 0.80 | GAA (0.57) | MAPTKDM4EGAATDP1L3MBTL1 | |
| SCHEMBL15764867 | 0.77 | MAPT (0.46) | MAPTKDM4EGAATDP1L3MBTL1 | |
| SCHEMBL14845761 | 0.76 | GAA (0.61) | MAPTKDM4EGAATDP1L3MBTL1 | |
| SCHEMBL8149846 | 0.76 | CA2 (0.64) | MAPTKDM4EGAATDP1L3MBTL1 | |
| SCHEMBL17807515 | 0.76 | GAA (0.52) | MAPTKDM4EGAATDP1L3MBTL1 | |
| SCHEMBL15075265 | 0.75 | GAA (0.55) | MAPTKDM4EGAATDP1L3MBTL1 | |
| SCHEMBL4889389 | 0.74 | GAA (0.59) | MAPTKDM4EGAATDP1L3MBTL1 | |
| SCHEMBL9676821 | 0.74 | GAA (0.59) | MAPTKDM4EGAATDP1L3MBTL1 | |
| SCHEMBL17322787 | 0.74 | GAA (0.59) | MAPTKDM4EGAATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160160215-A1 | POLYNUCLEOTIDES FOR MULTIVALENT RNA INTERFERENCE, COMPOSITIONS AND METHODS OF USE THEREOF | HALO BIO RNAI THERAPEUTICS INC (US) | 2016-06-09 | — | — | US | disclosed |
| WO-2012097091-A2 | ENGINEERED MICROORGANISMS WITH ENHANCED FERMENTATION ACTIVITY | VERDEZYNE, INC. (US) | 2012-07-19 | — | — | WO | disclosed |