Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.41 |
| ▸ | EDNRA | P25101 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17807515 | 0.89 | GAA (0.52) | GAAKDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL14845761 | 0.82 | GAA (0.61) | GAAKDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL8149846 | 0.82 | CA2 (0.64) | GAAKDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL12698753 | 0.82 | KDM4E (0.47) | GAAKDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL9676821 | 0.81 | GAA (0.59) | GAAKDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL17322787 | 0.81 | GAA (0.59) | GAAKDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL30116330 | 0.81 | GAA (0.59) | GAAKDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL4889389 | 0.81 | GAA (0.59) | GAAKDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL10344242 | 0.80 | MAPT (0.49) | GAAKDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL15631840 | 0.79 | GAA (0.57) | GAAKDM4EMAPTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238231-B1 | TRANSGENIC PHOTOSYNTHETIC MICROORGANISMS AND PHOTOBIOREACTOR | PROTERRO INC (US) | 2016-03-23 | — | — | EP | disclosed |
| US-9205144-B2 | Identification of conserved peptide blocks in homologous polypeptides | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-12-08 | — | — | US | disclosed |
| US-20150231132-A1 | PROCASPASE-ACTIVATING COMPOUNDS AND METHODS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2015-08-20 | — | — | US | disclosed |
| WO-2014179765-A2 | NOVEL HUMAN MIRNAS FOR USE IN DIAGNOSIS, PROGNOSIS AND THERAPY OF HUMAN CONDITIONS AND DISEASES | THOMAS JEFFERSON UNIVERSITY (US) | 2014-11-06 | — | — | WO | disclosed |
| US-8518031-B2 | Systems, devices and methods for making or administering frozen particles | THE INVENTION SCIENCE FUND I, LLC (US) | 2013-08-27 | — | — | US | disclosed |
| US-20130177558-A1 | Method of Treating Immunological Disorders by Administering Truncated BAFF Receptors | BIOGEN IDEC MA INC. (US) | 2013-07-11 | — | — | US | disclosed |
| US-20130064843-A1 | Identification of conserved peptide blocks in homologous polypeptides | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2013-03-14 | — | — | US | disclosed |
| WO-2012131078-A1 | BISPECIFIC BINDING MOLECULES BINDING TO VEGF AND ANG2 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-10-04 | — | — | WO | disclosed |
| US-8114601-B2 | Highly conserved genes and their use to generate probes and primers for detection of microorganisms | GENEOHM SCIENCES CANADA INC. (CA) | 2012-02-14 | — | — | US | disclosed |
| US-8110373-B2 | Methods and compositions for treating and diagnosing diseases | Celera Corporation (US) | 2012-02-07 | — | — | US | disclosed |
| US-7675770-B2 | Phase change memory device | ELPIDA MEMORY, INC. (JP) | 2010-03-09 | — | — | US | disclosed |
| EP-1501551-B1 | Folate-receptor targeted imaging agents | ENDOCYTE INC (US) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150231132-A1 | PROCASPASE-ACTIVATING COMPOUNDS AND METHODS | CASP3, CASP5, CASP6 | GAA 414/4885KDM4E 1115/4885MAPT 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.