Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15631840 | 0.86 | GAA (0.57) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL8149846 | 0.85 | CA2 (0.64) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL4889389 | 0.84 | GAA (0.59) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL9676821 | 0.84 | GAA (0.59) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL30116330 | 0.84 | GAA (0.59) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL17322787 | 0.84 | GAA (0.59) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL10048751 | 0.82 | GAA (0.57) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL15075265 | 0.81 | GAA (0.55) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL14142748 | 0.81 | GAA (0.55) | GAAMAPTKDM4ECA2HTR6 | |
| SCHEMBL13677633 | 0.81 | MAPT (0.55) | GAAMAPTKDM4ECA2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3248986-A2 | IMMUNOGLOBULIN VARIABLE DOMAINS | Ablynx NV (BE) | 2017-11-29 | — | — | EP | disclosed |
| US-9771614-B2 | High throughput nucleic acid sequencing by expansion and related methods | STRATOS GENOMICS INC. (US) | 2017-09-26 | — | — | US | disclosed |
| EP-3213748-A1 | CANNABINOIDS (THC:CBD RATIO) IN COMBINATION WITH AN ALKYLATING AGENT FOR USE IN TREATING BRAIN TUMOUR | GW Pharma Limited (GB) | 2017-09-06 | — | — | EP | disclosed |
| WO-2016168633-A1 | INDAZOLONES AS MODULATORS OF TNF SIGNALING | ABBVIE INC. (US) | 2016-10-20 | — | — | WO | disclosed |
| US-9373549-B2 | Semiconductor device and method of forming the same | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2016-06-21 | — | — | US | disclosed |
| US-9060931-B2 | Compositions and methods for delivery of frozen particle adhesives | THE INVENTION SCIENCE FUND I, LLC (US) | 2015-06-23 | — | — | US | disclosed |
| EP-2516462-B1 | IMMUNO-CONJUGATES AND METHODS FOR PRODUCING THEM | AVIPEP PTY LTD (AU) | 2015-05-06 | — | — | EP | disclosed |
| EP-2200634-B1 | TARGETED INTERFERON DEMONSTRATES POTENT APOPTOTIC AND ANTI-TUMOR ACTIVITIES | UNIV CALIFORNIA (US) | 2015-02-11 | — | — | EP | disclosed |
| WO-2014179765-A2 | NOVEL HUMAN MIRNAS FOR USE IN DIAGNOSIS, PROGNOSIS AND THERAPY OF HUMAN CONDITIONS AND DISEASES | THOMAS JEFFERSON UNIVERSITY (US) | 2014-11-06 | — | — | WO | disclosed |
| US-8865463-B2 | Generation of patient-specific differentiated cell types by epigenetic induction | GOPAL THIRU VENKAT (US) | 2014-10-21 | — | — | US | disclosed |
| US-8858912-B2 | Frozen compositions and methods for piercing a substrate | THE INVENTION SCIENCE FUND I, LLC (US) | 2014-10-14 | — | — | US | disclosed |
| WO-2014145873-A2 | HETEROCYCLIC COMPOUNDS USEFUL IN THE TREATMENT OF DISEASE | EPIGEN BIOSCIENCES, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| US-8798932-B2 | Frozen compositions and methods for piercing a substrate | THE INVENTION SCIENCE FUND I, LLC (US) | 2014-08-05 | — | — | US | disclosed |
| WO-2014042773-A1 | SYSTEMS AND METHODS FOR MITIGATING THE EFFECTS OF TISSUE BLOOD VOLUME CHANGES TO AID IN DIAGNOSING INFILTRATION OR EXTRAVASATION IN ANIMALIA TISSUE | IVWATCH, LLC (US) | 2014-03-20 | — | — | WO | disclosed |
| US-8623611-B2 | Glycoprotein cancer biomarker | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8518031-B2 | Systems, devices and methods for making or administering frozen particles | THE INVENTION SCIENCE FUND I, LLC (US) | 2013-08-27 | — | — | US | disclosed |
| US-8485861-B2 | Systems, devices, and methods for making or administering frozen particles | THE INVENTION SCIENCE FUND I, LLC (US) | 2013-07-16 | — | — | US | disclosed |
| US-8414356-B2 | Systems, devices, and methods for making or administering frozen particles | THE INVENTION SCIENCE FUND I, LLC (US) | 2013-04-09 | — | — | US | disclosed |