SCHEMBL10344601

SCHEMBL10344601

COc1cc(NC(=O)Nc2ccccc2)ccn1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.63
ALDH1A1 P00352 2/20 0.57
TAAR1 Q96RJ0 1/20 0.56
SMN1; SMN2 Q16637 4/20 0.54
KMT2A Q03164 3/20 0.54
PKM P14618 1/20 0.54
KCNK3 O14649 1/20 0.53
KCNK9 Q9NPC2 1/20 0.53
MEN1 O00255 2/20 0.52
MAPT P10636 1/20 0.52
TP53 P04637 3/20 0.52
TSHR P16473 2/20 0.52
EPHX1 P07099 1/20 0.52
EPHX2 P34913 1/20 0.52
CDK9 P50750 1/20 0.52
CLK4 Q9HAZ1 1/20 0.52
KDR P35968 3/20 0.51
IDO1 P14902 1/20 0.51
PDGFRA P16234 1/20 0.51
SORT1 Q99523 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21750831 0.87 CNR1 (0.58) CNR1ALDH1A1SMN1; SMN2KMT2APKM
SCHEMBL29557049 0.86 CNR1 (0.58) CNR1ALDH1A1SMN1; SMN2KMT2APKM
SCHEMBL29556137 0.86 RAB9A (0.64) CNR1ALDH1A1TAAR1SMN1; SMN2KMT2A
SCHEMBL29556058 0.86 CNR1 (0.68) CNR1ALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL11371907 0.85 CYP1A2 (0.55) ALDH1A1SMN1; SMN2KMT2AMEN1MAPT
SCHEMBL11342623 0.84 SMN1; SMN2 (0.59) CNR1ALDH1A1TAAR1SMN1; SMN2KMT2A
SCHEMBL15880285 0.84 SORT1 (0.55) CNR1ALDH1A1KMT2AKCNK3KCNK9
SCHEMBL113971 0.84 KCNK9 (0.66) SMN1; SMN2KMT2AKCNK3KCNK9MEN1
SCHEMBL22125487 0.84 SMARCA2 (0.67) CNR1ALDH1A1SMN1; SMN2KMT2AKCNK3
SCHEMBL29555952 0.82 CNR1 (0.60) CNR1ALDH1A1KMT2AKCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022078533-A1 SUBSTITUTED 1,3-DIPHENYLUREA DERIVATIVES AND 1-PHENYL-3-PYRIDYLUREA DERIVATIVES FOR PLANT BIOTECHNOLOGY, PREPARATIONS CONTAINING THESE COMPOUNDS AND USE THEREOF USTAV EXPERIMENTALNI BOTANIKY AV CR, V.V.I. (CZ) 2022-04-21 WO claimed
EP-0010770-B1 4-PYRIDYL UREAS OR THIOUREAS SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND PLANT GROWTH REGULANTS CONTAINING THEM Shudo, Koichi, Prof. Dr. (JP) 1982-07-07 EP claimed
US-4279639-A N-(2-Substituted-4-pyridyl)ureas and thioureas as well as plant growth regulators containing same, and method for using compounds as plant growth regulators Okamoto, Toshihiko (JP) 1981-07-21 US claimed
JP-55062066-A None JP disclosed
WO-2025226843-A1 METHOD, DEVICE, KIT, AND SYSTEM FOR MANUFACTURING PARTICLES BY CENTRIFUGATION FENG PRO LUN (US) 2025-10-30 WO disclosed
EP-4558508-A1 COMPOSITIONS FOR MODULATING LIPOXYGENASE AND METHODS OF USING SAME The Regents of the University of California (US) 2025-05-28 EP disclosed
WO-2024019959-A1 COMPOSITIONS FOR MODULATING LIPOXYGENASE AND METHODS OF USING SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-25 WO disclosed
US-20200383331-A1 COMPOSITIONS AND METHODS FOR LARGE-SCALE IN VITRO PLANT BIOCULTURE BOOSHOOT LLC (US) 2020-12-10 US disclosed
WO-2013016198-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR MICROPROPAGATION OF PLANTS BOOSHOOT LLC (US) 2013-01-31 WO disclosed
WO-2012097380-A1 COMPOSITIONS AND METHODS FOR BAMBOO PULPING The Red Triangle, LLC (US) 2012-07-19 WO disclosed
US-4279639-A N-(2-Substituted-4-pyridyl)ureas and thioureas as well as plant growth regulators containing same, and method for using compounds as plant growth regulators Okamoto, Toshihiko (JP) 1981-07-21 US disclosed
EP-0010770-A1 4-Pyridyl ureas or thioureas substituted in position 2, process for their preparation and plant growth regulants containing them Shudo, Koichi, Prof. Dr. (JP) 1980-05-14 EP disclosed
JP-S5562066-A N-(2-SUBSTITUTED-4-PYRIDYL)-UREA AND THIO UREA, THEIR PREPARATION AND PLANT GROWTH REGULATOR OKAMOTO TOSHIHIKO 1980-05-10 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200383331-A1 COMPOSITIONS AND METHODS FOR LARGE-SCALE IN VITRO PLANT BIOCULTURE MYB, MYCBP, PIM1 CNR1 64/4885ALDH1A1 4628/4885TAAR1 3006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.