SCHEMBL10344693

SCHEMBL10344693

CON(C)C(=O)Nc1c[c]c(Cl)cc1

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.65
RAB9A P51151 1/20 0.65
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
TSHR P16473 1/20 0.42
APEX1 P27695 1/20 0.40
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
EPHX2 P34913 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10800714 0.84 TSHR (0.61) PKMRAB9ATSHRAPEX1
SCHEMBL10344966 0.83 MEN1 (0.58) PKMRAB9AMEN1KMT2ATDP1
Monolinuron SCHEMBL1701381 0.79 RAB9A (1.00) PKMRAB9AMEN1KMT2ATDP1
Monolinuron SCHEMBL65568 0.79 RAB9A (1.00) PKMRAB9AMEN1KMT2ATDP1
SCHEMBL10344493 0.78 RAB9A (0.59) PKMRAB9AMEN1KMT2ATDP1
SCHEMBL10344723 0.76 PKM (0.61) PKMRAB9AMEN1KMT2ATDP1
SCHEMBL95120 0.75 SMN1; SMN2 (0.50) RAB9AMEN1KMT2ATDP1TSHR
Linuron SCHEMBL8406948 0.75 KMT2A (0.76) PKMRAB9AMEN1KMT2ATDP1
Linuron SCHEMBL56566 0.75 KMT2A (0.76) PKMRAB9AMEN1KMT2ATDP1
Monolinuron SCHEMBL8337749 0.75 PKM (0.90) PKMRAB9AMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192111-B1 ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
US-4692187-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
EP-0192111-A1 Iso-ureas, processes for their production and their use as herbicides BASF Aktiengesellschaft (DE) 1986-08-27 EP disclosed