Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.36 |
| ▸ | CA9 | Q16790 | 7/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA3 | P07451 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 3/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110031 | 0.85 | MCL1 (0.38) | CA12CA9CA2CA3CA4 | |
| SCHEMBL8520516 | 0.82 | MCL1 (0.36) | CA12CA9CA2CA3CA4 | |
| SCHEMBL21173972 | 0.77 | TDP1 (0.33) | CA12CA9CA2CA3CA4 | |
| Ethylene Glycol SCHEMBL9063623 | 0.72 | CYP1A2 (0.41) | CA12CA9CA2CA3CA4 | |
| SCHEMBL31481273 | 0.70 | ELANE (0.52) | NPC1HPGDKDM4EALDH1A1LMNA | |
| SCHEMBL21173933 | 0.69 | HSD17B10 (0.35) | CA12CA9CA2CA3CA4 | |
| SCHEMBL30525501 | 0.67 | CA12 (0.52) | CA12CA9CA2CA3CA4 | |
| SCHEMBL31025596 | 0.65 | GPR35 (0.34) | HPGDKDM4EALDH1A1HSD17B10AKR1B1 | |
| Isopropyl Alcohol SCHEMBL28725228 | 0.65 | HSD17B3 (0.32) | CA12CA9CA2CA3CA4 | |
| SCHEMBL10589100 | 0.65 | CA12 (0.50) | CA12CA9CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171152-B1 | ELECTROMAGNETIC RADIATION SUPPRESSING DISTRIBUTOR | GENERAL MOTORS CORPORATION (US) | 1990-05-16 | — | — | EP | disclosed |
| US-4575593-A | Electromagnetic radiation suppressing distributor rotors | GENERAL MOTORS CORPORATION (US) | 1986-03-11 | — | — | US | disclosed |