SCHEMBL8520516

SCHEMBL8520516

O=c1oc(=O)c2ccc(cc2)c2ccc1cc2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 5/20 0.36
CA12 O43570 5/20 0.36
CA9 Q16790 5/20 0.36
TDP1 Q9NUW8 4/20 0.36
LMNA P02545 3/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
SOST Q9BQB4 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
HSD17B3 P37058 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 4/20 0.32
HPGD P15428 4/20 0.32
KDM4E B2RXH2 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL110031 0.96 MCL1 (0.38) MCL1CA12CA9TDP1LMNA
SCHEMBL21173972 0.87 TDP1 (0.33) MCL1CA12CA9TDP1LMNA
Ethylene Glycol SCHEMBL10344735 0.82 CA12 (0.36) MCL1CA12CA9TDP1LMNA
SCHEMBL31481273 0.80 ELANE (0.52) TDP1LMNAL3MBTL1ALDH1A1HPGD
SCHEMBL21173933 0.78 HSD17B10 (0.35) MCL1CA12CA9TDP1LMNA
SCHEMBL376499 0.76 CA12 (0.52) MCL1CA12CA9TDP1LMNA
SCHEMBL30525501 0.76 CA12 (0.52) MCL1CA12CA9TDP1LMNA
SCHEMBL31025596 0.74 GPR35 (0.34) ALDH1A1HPGDKDM4EHSD17B10AKR1B1
SCHEMBL10589100 0.74 CA12 (0.50) MCL1CA12CA9TDP1LMNA
SCHEMBL9238549 0.69 CA1 (0.41) CA9CA1KDM4EHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773844-A Polyimide toughened phthalonitrile resin composition, composite material and preparation method thereof 北京玻钢院复合材料有限公司 2022-07-22 CN claimed
EP-0755375-B1 AQUEOUS PROCESS FOR PREPARING AMIDO-CARBOXYLIC ACIDS BY REACTING AN AMINO ACID WITH A CARBOXYLIC ACID ANHYDRIDE EASTMAN CHEM CO (US) 1999-10-13 EP claimed
EP-0755375-A1 AQUEOUS PROCESS FOR PREPARING AMIDO-CARBOXYLIC ACIDS BY REACTING AN AMINO ACID WITH A CARBOXYLIC ACID ANHYDRIDE EASTMAN CHEMICAL COMPANY (US) 1997-01-29 EP claimed
WO-1995028381-A1 AQUEOUS PROCESS FOR PREPARING AMIDO-CARBOXYLIC ACIDS BY REACTING AN AMINO ACID WITH A CARBOXYLIC ACID ANHYDRIDE EASTMAN CHEMICAL COMPANY (US) 1995-10-26 WO claimed
US-5391780-A Heating a mixture of water and lactam to hydrolyze; cooling; amididation by a carboxylic anhydride; separation of water and organic layer-containing product EASTMAN CHEMICAL COMPANY (US) 1995-02-21 US claimed
CN-120132069-A Medical polyimide catheter with developing function and preparation method and application thereof 宁波琳盛高分子材料有限公司 2025-06-13 CN disclosed
CN-118852621-A Polyimide compound, medical polyimide catheter, and preparation methods and applications thereof 宁波琳盛高分子材料有限公司 2024-10-29 CN disclosed
CN-115304579-B Preparation method of 4,4' -biphenyl dithioanhydride 河北海力恒远新材料股份有限公司 2023-10-31 CN disclosed
CN-115304579-B Preparation method of 4,4' -biphenyl dithioanhydride 河北海力恒远新材料股份有限公司 2023-10-31 CN disclosed
CN-113412299-B Polyamic acid and polyimide, optical film and display device, and method for producing same 中央硝子株式会社 2023-08-18 CN disclosed
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN disclosed
CN-115304579-A Preparation method of 4,4' -biphenyl disulfuric anhydride 河北海力香料股份有限公司 2022-11-08 CN disclosed
WO-2019170529-A1 METHOD FOR PRODUCING FIBRES, FILMS AND MOULDED BODIES OF A POLYBENZAZOLE POLYMER (P) BASF SE (DE) 2019-09-12 WO disclosed
EP-3512905-A1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2019-07-24 EP disclosed
EP-0755375-B1 AQUEOUS PROCESS FOR PREPARING AMIDO-CARBOXYLIC ACIDS BY REACTING AN AMINO ACID WITH A CARBOXYLIC ACID ANHYDRIDE EASTMAN CHEM CO (US) 1999-10-13 EP disclosed
EP-0755375-A1 AQUEOUS PROCESS FOR PREPARING AMIDO-CARBOXYLIC ACIDS BY REACTING AN AMINO ACID WITH A CARBOXYLIC ACID ANHYDRIDE EASTMAN CHEMICAL COMPANY (US) 1997-01-29 EP disclosed
WO-1995028381-A1 AQUEOUS PROCESS FOR PREPARING AMIDO-CARBOXYLIC ACIDS BY REACTING AN AMINO ACID WITH A CARBOXYLIC ACID ANHYDRIDE EASTMAN CHEMICAL COMPANY (US) 1995-10-26 WO disclosed
US-5391780-A Heating a mixture of water and lactam to hydrolyze; cooling; amididation by a carboxylic anhydride; separation of water and organic layer-containing product EASTMAN CHEMICAL COMPANY (US) 1995-02-21 US disclosed
US-4119776-A Vinyl phthalide color formers NCR CORPORATION (US) 1978-10-10 US disclosed
US-4022771-A RECORD MATERIALS AND MARKING SYSTEMS NCR CORPORATION (US) 1977-05-10 US disclosed