SCHEMBL10344902

SCHEMBL10344902

CC(=O)CNc1nc(C)c(Cl)s1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
RAB9A P51151 4/20 0.39
NPC1 O15118 3/20 0.39
RXFP1 Q9HBX9 3/20 0.36
HPGD P15428 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP1A2 P05177 1/20 0.34
GAA P10253 1/20 0.34
CYP2C9 P11712 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
POLB P06746 1/20 0.34
DHODH Q02127 1/20 0.34
PTGS2 P35354 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3823010 0.74 RAB9A (0.44) ALDH1A1RAB9ANPC1RXFP1HPGD
SCHEMBL10344901 0.72 TP53 (0.53) ALDH1A1RAB9ANPC1RXFP1HPGD
SCHEMBL14489682 0.69
SCHEMBL4097870 0.67 MAPT (0.51) ALDH1A1RAB9ANPC1HPGDMEN1
SCHEMBL1860027 0.63 SMN1; SMN2 (0.67) ALDH1A1RAB9ANPC1HPGDKMT2A
SCHEMBL10671313 0.63 MAPT (0.54) ALDH1A1RAB9ANPC1RXFP1MEN1
SCHEMBL2076096 0.63 ALDH1A1 (0.65) ALDH1A1RAB9ANPC1RXFP1HPGD
SCHEMBL2222371 0.63 ALDH1A1 (0.52) ALDH1A1RAB9ANPC1HPGDKDM4E
SCHEMBL24074024 0.62 RAB9A (0.56) ALDH1A1RAB9ANPC1RXFP1HPGD
SCHEMBL8556702 0.62 MAPK14 (0.48) ALDH1A1RAB9ANPC1RXFP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192111-B1 ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
EP-0121129-B1 2,5-DIHYDRO-5-ARYLIMINO-PYRROLES, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS HERBICIDES BASF Aktiengesellschaft (DE) 1989-02-01 EP disclosed
US-4789747-A BROAD LEAF PLANTS, GRASSES, WEEDS BASF AKTIENGESELLSCHAFT (DE) 1988-12-06 US disclosed
US-4761175-A M-anilido-urethanes and herbicides containing these compounds BASF AKTIENGESELLSCHAFT (DE) 1988-08-02 US disclosed
US-4744812-A HALOGENATED DIPHENYL ETHER BASF AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed
US-4726837-A Use of 4H-pyrido[2,3-d][1,3]oxazin-4-one derivatives for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1988-02-23 US disclosed
US-4715889-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
US-4692187-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
US-4632696-A POSTEMERGENCE, PREEMERGENCE APPLICATIONS BASF AKTIENGESELLSCHAFT (DE) 1986-12-30 US disclosed
EP-0192111-A1 Iso-ureas, processes for their production and their use as herbicides BASF Aktiengesellschaft (DE) 1986-08-27 EP disclosed
US-4360672-A Substituted phenoxyphenyl pyridazones, their preparation, and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1982-11-23 US disclosed
EP-0060429-A1 Dichloroquinoline derivatives, their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1982-09-22 EP disclosed
US-4343648-A 6H-1,2,4,6-THIATRIAZINE-1,1-DIOXIDES BASF AKTIENGESELLSCHAFT (DE) 1982-08-10 US disclosed
US-4340418-A Herbicidal agents based on N-azolylmethylacetanilides and cyclohexane-1,3-dione derivatives BASF AKTIENGESELLSCHAFT (DE) 1982-07-20 US disclosed
EP-0019760-B1 ESTERS OF 3-ARYL-5-METHYL-PYRAZOLE-4-CARBOXYLIC ACID, HERBICIDES CONTAINING THEM, PROCESS FOR THEIR PREPARATION AND THEIR USE BASF Aktiengesellschaft (DE) 1982-06-23 EP disclosed
EP-0024570-B1 5-IMINO-IMIDAZOLINE-2-ONES, HERBICIDES CONTAINING THEM AND PROCESS FOR DESTRUCTING UNDESIRED PLANTS BASF Aktiengesellschaft (DE) 1982-05-12 EP disclosed
US-4321371-A Substituted N-benzoylanthranilic acid derivatives and their anhydro compounds BASF AKTIENGESELLSCHAFT (DE) 1982-03-23 US disclosed
US-4316014-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US disclosed
EP-0019759-B1 N-ARYLTHIOLCARBAMATES, HERBICIDES CONTAINING THEM AND PROCESS FOR COMBATING UNDESIRABLE PLANT GROWTH THEREWITH BASF Aktiengesellschaft (DE) 1982-02-10 EP disclosed
EP-0021324-B1 M-ANILIDO URETHANES AND HERBICIDAL COMPOSITIONS WHICH CONTAIN THEM BASF Aktiengesellschaft (DE) 1982-01-20 EP disclosed