SCHEMBL10344901

SCHEMBL10344901

CCC(=O)Nc1nc(C)c(Cl)s1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.53
ALDH1A1 P00352 6/20 0.52
HPGD P15428 3/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
POLB P06746 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.51
RAB9A P51151 3/20 0.51
NPC1 O15118 2/20 0.51
PI4KB Q9UBF8 1/20 0.50
HSD17B10 Q99714 2/20 0.49
LMNA P02545 1/20 0.49
TSHR P16473 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
MAPT P10636 2/20 0.47
KDM4E B2RXH2 2/20 0.47
PKM P14618 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HTT P42858 1/20 0.45
CYP1A2 P05177 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19724747 0.82 MAPT (0.58) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL3823010 0.82 RAB9A (0.44) ALDH1A1HPGDMEN1KMT2APOLB
SCHEMBL19724917 0.79 TP53 (0.53) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL19724746 0.79 TP53 (0.53) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL28508629 0.78 ALDH1A1 (0.77) ALDH1A1HPGDMEN1KMT2APOLB
SCHEMBL3577082 0.78 ALDH1A1 (0.62) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL23774160 0.77 ALDH1A1 (0.50) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL19724720 0.76 ALDH1A1 (0.59) TP53ALDH1A1HPGDMEN1KMT2A
SCHEMBL24026376 0.74 ALDH1A1 (0.57) ALDH1A1HPGDMEN1KMT2ASMN1; SMN2
SCHEMBL9570921 0.73 ALDH1A1 (0.47) TP53ALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119338806-B Gear forging control method based on visual guidance 苏州昆仑重型装备制造有限公司 2025-05-13 CN claimed
CN-119538340-A Power transmission engineering GIM model analysis loading method, device, equipment and medium 山东鲁软数字科技有限公司 2025-02-28 CN claimed
CN-118739935-A Method and device for improving low-speed performance of high-power induction motor under control of no-speed sensor 中国矿业大学 2024-10-01 CN claimed
US-12057610-B2 Membrane electrode with ultra-low oxygen mass transfer resistance SHANGHAI JIAO TONG UNIVERSITY (CN) 2024-08-06 US claimed
CN-113687200-B Plane transformer testing die and testing method thereof 惠州市特创电子科技股份有限公司 2024-07-26 CN claimed
CN-117198287-B A voice recognition system for human-computer interaction of agent 南京汇智互娱网络科技有限公司 2024-07-05 CN claimed
CN-221042803-U Circuit for removing upper and lower electric noise of audio signal 立昇智能科技(上海)有限公司 2024-05-28 CN claimed
CN-118069352-A Parallel computing method and system for marine profile observation profile quality control process 中国科学院计算机网络信息中心 2024-05-24 CN claimed
CN-117904153-A Isopentenyl transferase gene CmPT for catalyzing prenylation and application thereof 中国药科大学 2024-04-19 CN claimed
CN-117876552-A Oblique photography three-dimensional model rendering method, computer device and storage medium 睿宇时空科技(重庆)股份有限公司 2024-04-12 CN claimed
CN-117198287-A A voice recognition system for human-computer interaction of agent 南京汇智互娱网络科技有限公司 2023-12-08 CN claimed
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2023-11-02 US claimed
CN-111354084-B Network geographic information service system based on three-dimensional model tiles 中国电建集团昆明勘测设计研究院有限公司 2023-07-14 CN claimed
CN-115035265-B Sketchup scene-to-three-dimensional geospatial conversion method, terminal and storage medium 深圳市万维云数字科技有限公司 2023-07-07 CN claimed
CN-115861172-A Wall motion estimation method and device based on self-adaptive regularized optical flow model 浙江大学医学院附属第四医院 2023-03-28 CN claimed
CN-217533239-U Unmanned aerial vehicle for power transmission line inspection with miniature 5G base station on body 三峡大学 2022-10-04 CN claimed
CN-115035265-A SketchUp scene-to-three-dimensional geographic space conversion method, terminal and storage medium 深圳市万维云数字科技有限公司 2022-09-09 CN claimed
CN-112989458-B Method for converting BIM (building information modeling) model into 3DTiles file 中铁二院工程集团有限责任公司 2022-09-06 CN claimed
CN-114429512-A Fusion display method and device for BIM and live-action three-dimensional model of coal preparation plant 中国中煤能源集团有限公司 2022-05-03 CN claimed
CN-113986791-A Intelligent network card rapid DMA design method, system, equipment and terminal 西安电子科技大学 2022-01-28 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION POLRMT, DCLRE1B, RNGTT TP53 1024/4885ALDH1A1 3318/4885HPGD 4878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.