Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | SLC18A2 | Q05940 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621060 | 0.87 | MAPT (0.35) | KDM4EALDH1A1GLAMAOAHTR2C | |
| SCHEMBL9620992 | 0.84 | HTR2A (0.33) | KDM4EALDH1A1GLAMAOASLC18A2 | |
| SCHEMBL9620907 | 0.82 | ACHE (0.41) | KDM4EALDH1A1GLAMAOAHTR2C | |
| SCHEMBL9620977 | 0.80 | MAOA (0.47) | KDM4EALDH1A1GLAMAOA | |
| SCHEMBL9620717 | 0.79 | HRH3 (0.37) | MAOA | |
| SCHEMBL9620752 | 0.78 | PDE4B (0.34) | KDM4EALDH1A1GLAMAOAHTR2C | |
| SCHEMBL9620922 | 0.77 | PDE4B (0.41) | KDM4EALDH1A1GLAMAOAHTR2C | |
| SCHEMBL9620956 | 0.76 | HTR2A (0.32) | SLC18A2HTR2CHTR2B | |
| SCHEMBL9621094 | 0.75 | HTR2A (0.39) | KDM4EALDH1A1GLAMAOASLC18A2 | |
| SCHEMBL9621237 | 0.73 | ACHE (0.39) | KDM4EALDH1A1HTR2CHTR2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369810-A2 | PAF antagonists as anti-hyperendothelinemia agents | Takeda Chemical Industries, Ltd. (JP) | 1990-05-23 | — | — | EP | disclosed |
| EP-0368670-A1 | Trisubstituted piperazine compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-05-16 | — | — | EP | disclosed |