Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345951 | 0.89 | TRHR (0.54) | TRHR | |
| Azetirelin SCHEMBL4958204 | 0.85 | TRHR (0.62) | TRHR | |
| Azetirelin SCHEMBL27999417 | 0.85 | TRHR (0.62) | TRHR | |
| SCHEMBL7324766 | 0.85 | TRHR (0.53) | TRHR | |
| Azetirelin SCHEMBL10703548 | 0.85 | TRHR (0.62) | TRHR | |
| Azetirelin SCHEMBL7265691 | 0.85 | TRHR (0.62) | TRHR | |
| Azetirelin SCHEMBL250397 | 0.85 | TRHR (0.62) | TRHR | |
| SCHEMBL21219552 | 0.85 | TRHR (0.53) | TRHR | |
| Azetirelin SCHEMBL4960774 | 0.85 | TRHR (0.61) | TRHR | |
| Taltirelin SCHEMBL14280928 | 0.84 | TRHR (0.57) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171159-B1 | SUBSTITUTED AZETIDINONE COMPOUNDS, THEIR PREPARATION, AND MEDICAMENTS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1990-05-30 | — | — | EP | claimed |
| EP-0171159-A1 | Substituted azetidinone compounds, their preparation, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-02-12 | — | — | EP | claimed |
| EP-0171159-B1 | SUBSTITUTED AZETIDINONE COMPOUNDS, THEIR PREPARATION, AND MEDICAMENTS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |