Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324766 | 0.92 | TRHR (0.53) | TRHR | |
| Taltirelin SCHEMBL21219549 | 0.89 | TRHR (0.57) | TRHR | |
| Taltirelin SCHEMBL14280928 | 0.89 | TRHR (0.57) | TRHR | |
| Taltirelin SCHEMBL21219551 | 0.89 | TRHR (0.57) | TRHR | |
| SCHEMBL10345951 | 0.88 | TRHR (0.54) | TRHR | |
| Taltirelin SCHEMBL3188420 | 0.88 | TRHR (0.57) | TRHR | |
| SCHEMBL7326905 | 0.88 | TRHR (0.55) | TRHR | |
| SCHEMBL7331966 | 0.88 | TRHR (0.55) | TRHR | |
| SCHEMBL7328021 | 0.87 | TRHR (0.55) | TRHR | |
| SCHEMBL21243016 | 0.87 | TRHR (0.55) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3520795-B1 | COMPOSITION COMPRISING COMBINATION OF TRH ANALOG WITH ARUNDIC ACID, AND PHARMACEUTICALLY ACCEPTABLE SALT OF ARUNDIC ACID | BRIVENTION PHARMACEUTICAL SHANGHAI INC (CN) | 2023-06-14 | — | — | EP | disclosed |
| CN-113559102-B | Compositions comprising a combination of a TRH analogue and propyloctanoic acid and pharmaceutically acceptable salts of propyloctanoic acid | 布利本迅药业(上海)有限公司 | 2023-01-03 | — | — | CN | disclosed |
| US-10828303-B2 | Composition comprising combination of TRH analog with arundic acid, and pharmaceutically acceptable salt of arundic acid | Brivention Pharmaceutical (Shanghai) Inc. (CN) | 2020-11-10 | — | — | US | disclosed |
| US-20190240221-A1 | COMPOSITION COMPRISING COMBINATION OF TRH ANALOG WITH ARUNDIC ACID, AND PHARMACEUTICALLY ACCEPTABLE SALT OF ARUNDIC ACID | Brivention Pharmaceutical (Shanghai) Inc. (CN) | 2019-08-08 | — | — | US | disclosed |
| EP-3520795-A1 | COMPOSITION COMPRISING COMBINATION OF TRH ANALOG WITH ARUNDIC ACID, AND PHARMACEUTICALLY ACCEPTABLE SALT OF ARUNDIC ACID | Brivention Pharmaceutical (Shanghai) Inc. (CN) | 2019-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190240221-A1 | COMPOSITION COMPRISING COMBINATION OF TRH ANALOG WITH ARUNDIC ACID, AND PHARMACEUTICALLY ACCEPTABLE SALT OF ARUNDIC ACID | TRHR, TRHDE, CRH | TRHR 1/4885 |
| US-10828303-B2 | Composition comprising combination of TRH analog with arundic acid, and pharmaceutically acceptable salt of arundic acid | TRHR, TRHDE, CRH | TRHR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.