Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28434406 | 0.82 | GAA (0.52) | KDM4ELMNAHTTL3MBTL1MEN1 | |
| SCHEMBL9588998 | 0.81 | KDM4E (0.63) | CHRM1KDM4ELMNACHRM2CHRM3 | |
| Hydrochloric Acid SCHEMBL9588751 | 0.80 | KDM4E (0.61) | CHRM1KDM4ELMNACHRM2CHRM3 | |
| SCHEMBL9588393 | 0.79 | KDM4E (0.60) | CHRM1KDM4ELMNACHRM2CHRM3 | |
| Xenbucin SCHEMBL10345476 | 0.79 | PTGS2 (0.45) | KDM4EALDH1A1UTS2R | |
| Butetamate SCHEMBL1643343 | 0.78 | KDM4E (0.84) | CHRM1KDM4ELMNACHRM2CHRM3 | |
| SCHEMBL9588277 | 0.77 | KDM4E (0.78) | CHRM1KDM4ELMNACHRM2CHRM3 | |
| SCHEMBL9588408 | 0.76 | KDM4E (0.76) | CHRM1KDM4ELMNACHRM2CHRM3 | |
| SCHEMBL3954433 | 0.76 | KDM4E (0.62) | CHRM1KDM4ELMNAHTTL3MBTL1 | |
| Xenbucin SCHEMBL24134 | 0.75 | PTGS2 (0.58) | LMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105635-B1 | NONIRRITATING AQUEOUS OPHTHALMIC COMPOSITIONS COMFORT FORMULATION FOR OCULAR THEREPEUTIC AGENTS | ALCON LABORATORIES, INC. (US) | 1990-04-04 | — | — | EP | disclosed |
| US-4559343-A | ANTIINFLAMMATORY AGENT WITH XANTHINE DERIVATIVE | ALCON LABORATORIES, INC. (US) | 1985-12-17 | — | — | US | disclosed |
| EP-0105635-A2 | Nonirritating aqueous ophthalmic compositions comfort formulation for ocular therepeutic agents | ALCON LABORATORIES, INC. (US) | 1984-04-18 | — | — | EP | disclosed |