Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | LDHB | P07195 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1030858 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL1032229 | 0.88 | NISCH (0.32) | ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL1030885 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL1029407 | 0.87 | LDHA (0.33) | ADRA2AADRA2BADRA2CLDHALDHB | |
| Hydrochloric Acid SCHEMBL1031887 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL1032560 | 0.86 | PTGS2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL1031236 | 0.84 | CHRM3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL1034018 | 0.83 | NISCH (0.30) | — | |
| Hydrochloric Acid SCHEMBL1032897 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL1033185 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567560-B1 | ORGANOMETALLIC TRANSITION METAL COMPOUND, BISCYCLOPENTADIENYL LIGAND SYSTEM, CATALYST SYSTEM AND PROCESS FOR PREPARING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2011-01-19 | — | — | EP | disclosed |