Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.37 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2519175 | 0.85 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL13268818 | 0.81 | PI4KA (0.45) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL13269091 | 0.81 | PI4KA (0.45) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL5525776 | 0.81 | PI4KA (0.45) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL10345558 | 0.81 | ADORA3 (0.42) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL10345331 | 0.80 | ADORA3 (0.43) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL10345450 | 0.79 | ADORA3 (0.42) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL13268769 | 0.78 | INMT (0.43) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| Benzene SCHEMBL27650186 | 0.78 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL7435441 | 0.78 | ADORA3 (0.50) | PI4KAPI4K2BPI4K2API4KBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0179630-B1 | N6-ACENAPHTHYL ADENOSINES AND ANALOGS THEREOF | WARNER-LAMBERT COMPANY (US) | 1990-03-07 | — | — | EP | claimed |
| EP-0179630-A2 | N6-acenaphthyl adenosines and analogs thereof | WARNER-LAMBERT COMPANY (US) | 1986-04-30 | — | — | EP | claimed |
| EP-0179630-B1 | N6-ACENAPHTHYL ADENOSINES AND ANALOGS THEREOF | WARNER-LAMBERT COMPANY (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4663313-A | N6 -tricyclic adenosines for treating hypertension | WARNER-LAMBERT COMPANY (US) | 1987-05-05 | — | — | US | disclosed |