SCHEMBL10346409

SCHEMBL10346409

O=C(c1ccc(O)cc1)c1ccc(F)cc1.[KH]

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.71
MAPT P10636 3/20 0.71
ESR1 P03372 2/20 0.71
ESR2 Q92731 2/20 0.71
HPGD P15428 2/20 0.71
HTT P42858 2/20 0.71
PKM P14618 1/20 0.71
SRD5A2 P31213 1/20 0.60
LTA4H P09960 1/20 0.59
MAPK1 P28482 2/20 0.58
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
RAB9A P51151 3/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
NPC1 O15118 3/20 0.50
ALDH1A1 P00352 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL10635290 0.98 LMNA (0.75) LMNAMAPTESR1ESR2HPGD
SCHEMBL10631127 0.98 LMNA (0.75) LMNAMAPTESR1ESR2HPGD
SCHEMBL145363 0.98 LMNA (0.75) LMNAMAPTESR1ESR2HPGD
SCHEMBL10631102 0.98 LMNA (0.75) LMNAMAPTESR1ESR2HPGD
SCHEMBL4382240 0.98 LMNA (0.75) LMNAMAPTESR1ESR2HPGD
Hydroquinone SCHEMBL10631077 0.98 LMNA (0.75) LMNAMAPTESR1ESR2HPGD
SCHEMBL720142 0.91 LMNA (0.67) LMNAMAPTESR1ESR2HPGD
SCHEMBL10871402 0.91 LMNA (0.67) LMNAMAPTESR1ESR2HPGD
SCHEMBL238259 0.87 LTA4H (0.73) LMNAMAPTESR1ESR2HPGD
SCHEMBL7929114 0.87 LMNA (0.94) LMNAMAPTESR1ESR2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0193187-B1 PROCESS FOR PREPARING CRYSTALLINE AROMATIC POLYETHERKETONES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1990-06-13 EP disclosed
US-4757126-A Polycondensing 4,4'-dihydroxybenzophenone or hydroquinone with dihalogenoaromatic ketone in solvent in the presence of an alkali ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-07-12 US disclosed
EP-0193187-A1 Process for preparing crystalline aromatic polyetherketones Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-09-03 EP disclosed