Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 3/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.59 |
| ▸ | BAD | Q92934 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871402 | 1.00 | LMNA (0.67) | LMNAMAPTMEN1RAB9AKMT2A | |
| Hydroquinone SCHEMBL10631077 | 0.93 | LMNA (0.75) | LMNAMAPTMEN1RAB9AKMT2A | |
| SCHEMBL4382240 | 0.93 | LMNA (0.75) | LMNAMAPTMEN1RAB9AKMT2A | |
| SCHEMBL10631127 | 0.93 | LMNA (0.75) | LMNAMAPTMEN1RAB9AKMT2A | |
| SCHEMBL10631102 | 0.93 | LMNA (0.75) | LMNAMAPTMEN1RAB9AKMT2A | |
| SCHEMBL145363 | 0.93 | LMNA (0.75) | LMNAMAPTMEN1RAB9AKMT2A | |
| Hydroquinone SCHEMBL10635290 | 0.93 | LMNA (0.75) | LMNAMAPTMEN1RAB9AKMT2A | |
| SCHEMBL10346409 | 0.91 | LMNA (0.71) | LMNAMAPTMEN1RAB9AKMT2A | |
| SCHEMBL9814506 | 0.91 | BCL2L1 (0.70) | LMNAMAPTMEN1RAB9AKMT2A | |
| SCHEMBL1864175 | 0.91 | BCL2L1 (0.70) | LMNAMAPTMEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023692-B2 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2018-07-17 | — | — | US | disclosed |
| EP-3147304-A1 | POLYMERIC MATERIALS | Victrex Manufacturing Limited (GB) | 2017-03-29 | — | — | EP | disclosed |
| EP-3144336-A1 | POLYMERIC MATERIALS | Victrex Manufacturing Limited (GB) | 2017-03-22 | — | — | EP | disclosed |
| US-20160145385-A1 | METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S IN THE PRESENCE OF SODIUM CARBONATE | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2016-05-26 | — | — | US | disclosed |
| US-9175136-B2 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2015-11-03 | — | — | US | disclosed |
| US-20140128566-A1 | POLYMERIC MATERIALS | VICTREX MANUFACTURING LIMITED (GB) | 2014-05-08 | — | — | US | disclosed |
| EP-2344565-B1 | METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S IN THE PRESENCE OF SODIUM CARBONATE | SOLVAY SPECIALTY POLYMERS USA (US) | 2014-03-19 | — | — | EP | disclosed |
| US-8445141-B2 | Sulfonic acid group-containing polymer, method for producing the same, resin composition containing such sulfonic acid group-containing polymer, polymer electrolyte membrane, polymer electrolyte membrane/electrode assembly, and fuel cell | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2013-05-21 | — | — | US | disclosed |
| US-8216727-B2 | Aromatic hydrocarbon based proton exchange membrane and direct methanol fuel cell using same | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20120052411-A9 | AROMATIC HYDROCARBON BASED PROTON EXCHANGE MEMBRANE AND DIRECT METHANOL FUEL CELL USING SAME | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |
| EP-1561768-A1 | POLYARYLENE ETHER COMPOUND CONTAINING SULFONIC ACID GROUP, COMPOSITION CONTAINING SAME, AND METHOD FOR MANUFACTURING THOSE | Toyo Boseki Kabushiki Kaisha (JP) | 2005-08-10 | — | — | EP | disclosed |
| US-4999414-A | Process for the production of aromatic polyether ketones | BAYER AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |
| EP-0193187-B1 | PROCESS FOR PREPARING CRYSTALLINE AROMATIC POLYETHERKETONES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-06-13 | — | — | EP | disclosed |
| EP-0354377-A2 | Process for the preparation of aromatic polyether ketones | BAYER AG (DE) | 1990-02-14 | — | — | EP | disclosed |
| US-4868273-A | SOLVENT RESISTANT POLYETHERS CONTAINING SULFONE AND CARBONYL GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-19 | — | — | US | disclosed |
| EP-0303389-A2 | Aromatic polymer | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-15 | — | — | EP | disclosed |
| US-4777300-A | Aromatic ketone | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-11 | — | — | US | disclosed |
| US-4757126-A | Polycondensing 4,4'-dihydroxybenzophenone or hydroquinone with dihalogenoaromatic ketone in solvent in the presence of an alkali | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0232019-A2 | Aromatic Polymer | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-08-12 | — | — | EP | disclosed |
| EP-0193187-A1 | Process for preparing crystalline aromatic polyetherketones | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023692-B2 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | PKM, KCNK10, KCNK9 | LMNA 1173/4885MAPT 3336/4885MEN1 4737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.