SCHEMBL103468

SCHEMBL103468

O=C(/N=N/C(=O)N1CCCCC1)N1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
HPGD P15428 4/20 0.44
MMP1 P03956 1/20 0.44
MMP2 P08253 1/20 0.44
MMP3 P08254 1/20 0.44
MMP9 P14780 1/20 0.44
CA2 P00918 2/20 0.42
CHKA P35790 1/20 0.42
ATM Q13315 1/20 0.40
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
F2 P00734 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
GAA P10253 1/20 0.37
HSD11B1 P28845 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10791 1.00 ALDH1A1 (0.52) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL12367675 1.00 ALDH1A1 (0.52) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL8951223 0.97 ALDH1A1 (0.48) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL2677860 0.97 ALDH1A1 (0.48) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL12489264 0.89 ALDH1A1 (0.48) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL13448727 0.86 ALDH1A1 (0.41) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL28463998 0.85 ALDH1A1 (0.48) ALDH1A1HPGDMMP1MMP2MMP3
Diamide SCHEMBL7203941 0.82 ALDH1A1 (0.52) ALDH1A1HPGDMMP1MMP2MMP3
Diamide SCHEMBL7203943 0.82 ALDH1A1 (0.52) ALDH1A1HPGDMMP1MMP2MMP3
SCHEMBL12713534 0.81 ALDH1A1 (0.45) ALDH1A1HPGDCA2POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4506 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250136605-A1 IMPROVED METHODS FOR PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES IMMUNOGEN, INC. 2025-05-01 US claimed
US-11981688-B2 Methods of preparing cytotoxic benzodiazepine derivatives IMMUNOGEN, INC. (US) 2024-05-14 US claimed
CN-116426127-B High-flame-retardance platinum catalyst and preparation method and application thereof 广州市矽友新材料科技有限公司 2024-05-03 CN claimed
EP-4361128-A2 METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES ImmunoGen, Inc. (US) 2024-05-01 EP claimed
EP-3880681-B1 METHODS OF PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES IMMUNOGEN INC (US) 2024-03-13 EP claimed
WO-2024025389-A1 METHOD FOR PREPARING INTERMEDIATE OF PHTHALAZINONE DERIVATIVE 아이디언스 주식회사 2024-02-01 WO claimed
EP-4265602-A2 LEOLIGIN DERIVATIVES AS PROLIFERATION INHIBITORS OF SMOOTH MUSCLE CELLS TECHNISCHE UNIVERSITÄT WIEN (AT) 2023-10-25 EP claimed
US-11779663-B2 Specific conjugation linkers, specific immunoconjugates thereof, methods of making and uses such conjugates thereof HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-10-10 US claimed
CN-114213652-B Preparation method of vinyl-terminated polyphenyl ether compound 河北健馨生物科技有限公司 2023-08-08 CN claimed
CN-116426127-A High-flame-retardance platinum catalyst and preparation method and application thereof 广州市矽友新材料科技有限公司 2023-07-14 CN claimed
US-20010041798-A1 Processes and intermediates in the synthesis of 5-(3-{exo-bicyclo{2.2.1}hept-2-yloxy]-4-methoxyphenyl)-3,4,5,6- tetrahydropyrimidin-2(1H)-one LACOUR THOMAS G (US) 2001-11-15 US claimed
US-6153633-A Stable 3-isothiazolone compositions ROHM AND HAAS COMPANY (US) 2000-11-28 US claimed
EP-0981959-A1 Stable 3-isothiazolone compositions ROHM AND HAAS COMPANY (US) 2000-03-01 EP claimed
US-6022968-A Processes for the synthesis of 5-(3-[exo-bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl)-3,4,5,6-tetrahydr opyrimidin-2(1H)-one PFIZER INC (US) 2000-02-08 US claimed
EP-0861240-A1 PROCESSES AND INTERMEDIATES FOR PREPARING 1-(2- 2-ISOXAZOL-3-YLBENZOFURAN-5-YLOXY]ETHYLAMINO)-3-PHENOXY-2(S)-OL PFIZER INC. (US) 1998-09-02 EP claimed
EP-0775119-A1 PROCESSES AND INTERMEDIATES IN THE SYNTHESIS OF 5-(3- EXO-BICYCLO 2.2.1]HEPT-2-YLOXY]-4-METHOXYPHENYL)-3,4,5,6-TETRAHYDROPYRIMIDIN-2(1H)-ONE PFIZER INC. (US) 1997-05-28 EP claimed
WO-1997016432-A1 PROCESSES AND INTERMEDIATES FOR PREPARING 1-(2-[2-ISOXAZOL-3-YLBENZOFURAN-5-YLOXY]ETHYLAMINO)-3-PHENOXY-2(S)-OL PFIZER INC. (US) 1997-05-09 WO claimed
US-5585367-A ANTISEPTIC VIRICIDE LIQUID MIXTURE COMPRISING AZOIC ACTIVE MATERIALS PREVISAN S.A. (LU) 1996-12-17 US claimed
US-5539102-A ANTIBIOTIC SYNTHESIS BY DEHYDRATION REACTION OF ALCOHOL WITH OXYCARBONYLSULFAMIDE IN THE PRESENCE OF TRIVALENT PHOSPHOROUS SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1996-07-23 US claimed
WO-1996004253-A1 PROCESSES AND INTERMEDIATES IN THE SYNTHESIS OF 5-(3-[EXO-BICYCLO[2.2.1]HEPT-2-YLOXY]-4-METHOXYPHENYL)-3,4,5,6-TETRAHYDROPYRIMIDIN-2(1H)-ONE PFIZER INC. (US) 1996-02-15 WO claimed