Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8951223 | 1.00 | ALDH1A1 (0.48) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL103468 | 0.97 | ALDH1A1 (0.52) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL12367675 | 0.97 | ALDH1A1 (0.52) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL10791 | 0.97 | ALDH1A1 (0.52) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL28463998 | 0.87 | ALDH1A1 (0.48) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL12489264 | 0.86 | ALDH1A1 (0.48) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL13448727 | 0.83 | ALDH1A1 (0.41) | ALDH1A1ATMHPGDMMP1MMP2 | |
| SCHEMBL12802471 | 0.81 | — | — | |
| Diamide SCHEMBL7203941 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| Diamide SCHEMBL7203943 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HPGDMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539102-A | ANTIBIOTIC SYNTHESIS BY DEHYDRATION REACTION OF ALCOHOL WITH OXYCARBONYLSULFAMIDE IN THE PRESENCE OF TRIVALENT PHOSPHOROUS | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-07-23 | — | — | US | claimed |
| EP-3129449-B1 | DIESEL FUEL WITH IMPROVED IGNITION CHARACTERISTICS | SHELL INT RESEARCH (NL) | 2018-03-28 | — | — | EP | disclosed |
| US-9862905-B2 | Diesel fuel with improved ignition characteristics | SHELL OIL COMPANY (US) | 2018-01-09 | — | — | US | disclosed |
| EP-3129449-A1 | DIESEL FUEL WITH IMPROVED IGNITION CHARACTERISTICS | Shell Internationale Research Maatschappij B.V. (NL) | 2017-02-15 | — | — | EP | disclosed |
| WO-2015157207-A1 | DIESEL FUEL WITH IMPROVED IGNITION CHARACTERISTICS | SHELL OIL COMPANY (US) | 2015-10-15 | — | — | WO | disclosed |
| US-20150284652-A1 | DIESEL FUEL WITH IMPROVED IGNITION CHARACTERISTICS | SHELL OIL COMPANY | 2015-10-08 | — | — | US | disclosed |
| US-8173824-B2 | Process for producing vitamin D derivative using convergent method | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-05-08 | — | — | US | disclosed |
| US-20100217020-A1 | PROCESS FOR PRODUCING VITAMIN D DERIVATIVE USING CONVERGENT METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-1955999-A1 | METHOD FOR PRODUCING VITAMIN D DERIVATIVE BY USING CONVERGENT METHOD | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-08-13 | — | — | EP | disclosed |
| EP-0557122-B1 | A production method for sulfamide | SHIONOGI & CO (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5539102-A | ANTIBIOTIC SYNTHESIS BY DEHYDRATION REACTION OF ALCOHOL WITH OXYCARBONYLSULFAMIDE IN THE PRESENCE OF TRIVALENT PHOSPHOROUS | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0557122-A1 | A production method for sulfamide | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1993-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100217020-A1 | PROCESS FOR PRODUCING VITAMIN D DERIVATIVE USING CONVERGENT METHOD | CYP2R1, CYP24A1, VDR | ALDH1A1 339/4885ATM 4463/4885HPGD 90/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.