Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diamide SCHEMBL7203941 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRMAPTNFKB1THPO | |
| SCHEMBL103468 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL10791 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL12367675 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL2677860 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTNFKB1THPOHSD17B10 | |
| SCHEMBL8951223 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTNFKB1THPOHSD17B10 | |
| Benzene SCHEMBL28227366 | 0.76 | HPGD (0.48) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL12489264 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDMMP1MMP2 | |
| SCHEMBL7338570 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPTGFERHPGD | |
| Diamide SCHEMBL103289 | 0.72 | TSHR (1.00) | ALDH1A1TSHRMAPTNFKB1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586452-B1 | Plant extracts used as miticides, parasiticides, insecticides and/or anthelmintics | MERCK & CO., INC. | 2003-07-01 | — | — | US | disclosed |
| EP-0545591-A1 | Heat curable organopolysiloxane compositions and preformed latent platinum catalysts | GENERAL ELECTRIC COMPANY (US) | 1993-06-09 | — | — | EP | disclosed |