Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | IAPP | P10997 | 3/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4138034 | 0.87 | CA1 (0.48) | HSD17B10KDM4EALOX15ALDH1A1HPGD | |
| SCHEMBL220009 | 0.84 | ESR1 (0.52) | HSD17B10KDM4EALOX15ALDH1A1HPGD | |
| SCHEMBL7171659 | 0.75 | ALDH1A1 (0.51) | HSD17B10KDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL10767943 | 0.75 | LMNA (0.54) | HSD17B10KDM4EALOX15ALDH1A1HPGD | |
| SCHEMBL27970317 | 0.74 | SMN1; SMN2 (0.53) | HSD17B10KDM4EALOX15ALDH1A1HPGD | |
| SCHEMBL3175245 | 0.74 | LMNA (0.52) | HSD17B10KDM4EALOX15ALDH1A1HPGD | |
| SCHEMBL3318373 | 0.73 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDLMNAMAPT | |
| SCHEMBL25386879 | 0.73 | ALDH1A1 (0.41) | KDM4EALDH1A1HTTGAAKMT2A | |
| SCHEMBL146449 | 0.71 | HRH1 (0.43) | KDM4ELMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL226234 | 0.70 | HTT (0.47) | KDM4EALOX15ALDH1A1LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212439-B1 | POLYMERS AND RADIOSENSITIVE COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-16 | — | — | EP | disclosed |
| EP-0212439-A2 | Polymers and radiosensitive compositions containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |