Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347948 | 0.84 | HSD17B10 (0.44) | ESR1ESR2KMT2AMEN1GAA | |
| SCHEMBL4138034 | 0.82 | CA1 (0.48) | ESR1ESR2KMT2AMEN1GAA | |
| SCHEMBL7171659 | 0.81 | ALDH1A1 (0.51) | KMT2AMEN1GAAHSD17B10POLB | |
| SCHEMBL217075 | 0.74 | ESR1 (0.49) | ESR1ESR2KMT2AMEN1GAA | |
| SCHEMBL3113592 | 0.73 | ESR1 (0.46) | ESR1ESR2KMT2AMEN1GAA | |
| SCHEMBL10458543 | 0.73 | ESR1 (0.69) | ESR1ESR2KMT2AMEN1GAA | |
| SCHEMBL8746649 | 0.70 | NFKB1 (0.67) | ESR1ESR2MAPTCA1CA2 | |
| SCHEMBL27970317 | 0.70 | SMN1; SMN2 (0.53) | KMT2AGAAHSD17B10MAPTALOX15 | |
| 1-Naphthol SCHEMBL11373502 | 0.69 | CYP1A2 (0.68) | ESR1ESR2KMT2AMEN1GAA | |
| SCHEMBL10959997 | 0.69 | KDM4E (0.67) | ESR1ESR2KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2384457-B1 | COATING COMPOSITIONS | MERCK PATENT GMBH (DE) | 2022-07-06 | — | — | EP | disclosed |
| EP-2718379-B1 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF | MERCK PATENT GMBH (DE) | 2016-08-17 | — | — | EP | disclosed |
| US-9146467-B2 | Coating compositions | MERCK PATENT GMBH (DE) | 2015-09-29 | — | — | US | disclosed |
| EP-2718379-A1 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF | AZ Electronic Materials USA Corp. (US) | 2014-04-16 | — | — | EP | disclosed |
| US-8623589-B2 | Bottom antireflective coating compositions and processes thereof | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2014-01-07 | — | — | US | disclosed |
| US-20130236833-A1 | COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2013-09-12 | — | — | US | disclosed |
| US-8455176-B2 | Coating composition | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2013-06-04 | — | — | US | disclosed |
| WO-2012168785-A1 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-12-13 | — | — | WO | disclosed |
| US-20120308939-A1 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AND PROCESSES THEREOF | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-12-06 | — | — | US | disclosed |
| WO-2012063120-A1 | UNDERLAYER DEVELOPABLE COATING COMPOSITIONS AND PROCESSES THEREOF | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-05-18 | — | — | WO | disclosed |
| US-20120122029-A1 | Underlayer Developable Coating Compositions and Processes Thereof | AZ ELECTRONIC MATERIALS USA CORP. | 2012-05-17 | — | — | US | disclosed |
| US-8088548-B2 | Bottom antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-2384457-A2 | COATING COMPOSITIONS | AZ Electronic Materials USA Corp. (US) | 2011-11-09 | — | — | EP | disclosed |
| EP-2212273-A2 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS | AZ Electronic Materials USA Corp. (US) | 2010-08-04 | — | — | EP | disclosed |
| WO-2010055406-A2 | COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2010-05-20 | — | — | WO | disclosed |
| US-20100119972-A1 | COATING COMPOSITION | MERCK PATENT GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
| WO-2009053832-A2 | BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (DE) | 2009-04-30 | — | — | WO | disclosed |
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104559-A1 | Bottom Antireflective Coating Compositions | SDC2, S100A9, MYH9 | ESR1 2135/4885ESR2 2409/4885KMT2A 1852/4885 |
| US-20100119972-A1 | COATING COMPOSITION | S100A9, CAPG, C5 | ESR1 2137/4885ESR2 1875/4885KMT2A 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.