Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564160 | 0.84 | MAPT (0.53) | PTPN1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10348927 | 0.83 | MAPK1 (0.55) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL21154227 | 0.73 | HTT (0.65) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL7534511 | 0.73 | ALDH1A1 (0.51) | PTPN1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28300026 | 0.71 | MEN1 (0.44) | KMT2AMEN1ALDH1A1HTTTP53 | |
| SCHEMBL2791913 | 0.71 | PTPN1 (0.69) | PTPN1SMN1; SMN2MAPK1DYRK1AFSCN1 | |
| SCHEMBL10348387 | 0.70 | TSHR (0.51) | MAPTKMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL2793299 | 0.70 | PTPN1 (0.66) | PTPN1MAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL14144251 | 0.69 | MAPT (0.43) | PTPN1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10654126 | 0.69 | PTPN1 (0.48) | PTPN1MAPTKMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163236-B1 | BENZOXAZOLYL AND BENZOTHIAZOLYL AMINOACIDS, THEIR PREPARATION AND THEIR USE IN THE PRESERVATION OF PLANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-25 | — | — | EP | claimed |
| US-4814459-A | REDUCING PHYTOTOXICITY OF HERBICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-21 | — | — | US | claimed |
| US-4814459-A | REDUCING PHYTOTOXICITY OF HERBICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-21 | — | — | US | disclosed |