Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025988 | 0.78 | MEN1 (0.45) | MEN1KMT2AHPGDALDH1A1TDP1 | |
| SCHEMBL3168456 | 0.77 | MAPT (0.49) | MEN1KMT2AHPGDALDH1A1GAA | |
| SCHEMBL28026747 | 0.76 | CYP3A4 (0.42) | MEN1KMT2APOLBTP53TSHR | |
| SCHEMBL20322977 | 0.74 | USP2 (0.41) | MEN1KMT2AALDH1A1PPARGUSP2 | |
| SCHEMBL21645061 | 0.73 | SMN1; SMN2 (0.44) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL8913104 | 0.73 | NLRP3 (0.49) | MEN1KMT2AHPGDALDH1A1TSHR | |
| SCHEMBL2949925 | 0.72 | ALDH1A1 (0.45) | KMT2AHPGDALDH1A1TSHRHTT | |
| SCHEMBL20322854 | 0.71 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1TDP1TSHR | |
| SCHEMBL10348145 | 0.71 | PTPN1 (0.54) | MEN1KMT2AHPGDALDH1A1POLB | |
| SCHEMBL7105765 | 0.71 | CYP4F2 (0.50) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776385-B | Preparation method of N-substituted isatin derivative | 浙江工业大学 | 2020-11-13 | — | — | CN | disclosed |
| CN-109776385-A | A kind of N- replaces the preparation method of Isatine derivatives | 浙江工业大学 | 2019-05-21 | — | — | CN | disclosed |