SCHEMBL1034834

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1034305	0.90	KMO (0.49)	SORT1KMOCNR1CNR2PIK3CD
	SCHEMBL1035365	0.82	PHGDH (0.46)	SORT1KMOPHGDHCNR1CNR2
	SCHEMBL1033871	0.81	FGFR4 (0.51)	KMOCNR2PARP1L3MBTL1FGFR4
	SCHEMBL1034072	0.81	JAK2 (0.51)	KMOCNR1CNR2L3MBTL1JAK2
	SCHEMBL1033800	0.81	KMO (0.47)	KMOKMT2A
	SCHEMBL1032901	0.81	NPC1 (0.50)	CNR1CNR2L3MBTL1NPC1RAB9A
	SCHEMBL17772340	0.81	DHODH (0.42)	SORT1KMOCNR1CNR2PIK3CD
	SCHEMBL1030361	0.81	AR (0.42)	SORT1KMOCNR1CNR2PIK3CD
	SCHEMBL1073743	0.81	ADORA2A (0.48)	SORT1KMOCNR1CNR2PIK3CD
	SCHEMBL1034065	0.81	RXFP1 (0.53)	PARP1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.