SCHEMBL1034305

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1034834	0.90	SORT1 (0.57)	KMOFGFR4CNR1CNR2MAPKAPK2
	SCHEMBL1033871	0.89	FGFR4 (0.51)	KMOSIRT2FGFR4CNR2MAPKAPK2
	SCHEMBL1034072	0.86	JAK2 (0.51)	KMOSIRT2CNR1CNR2MAPT
	SCHEMBL1031946	0.86	KDR (0.47)	KMOFGFR4MAPKAPK2MAPTEGLN1
	SCHEMBL1034065	0.86	RXFP1 (0.53)	PARP1MAPTRXFP1LMNAMEN1
	SCHEMBL1034835	0.85	SIRT2 (0.51)	KMOSIRT2MAPTALDH1A1LMNA
	SCHEMBL1034603	0.85	ALOX15 (0.59)	KMOSIRT2FGFR4CNR1CNR2
	SCHEMBL1035234	0.85	MPL (0.52)	KMOFGFR4CNR1CNR2MAPKAPK2
	SCHEMBL1033800	0.84	KMO (0.47)	KMOMAPTEGLN1RXFP1MEN1
	SCHEMBL1033391	0.83	SIRT2 (0.50)	KMOSIRT2FGFR4CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.