Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34472984 | 0.86 | ALDH1A1 (0.52) | TSHRALDH1A1HPGDCYP3A4MAPT | |
| SCHEMBL2830597 | 0.77 | ALB (0.55) | TSHRALDH1A1HPGDTTRDHODH | |
| SCHEMBL16616281 | 0.77 | CYP1A2 (0.50) | TSHRALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL27336447 | 0.76 | HPGD (0.52) | ALDH1A1LMNAKMT2AHPGDCYP1A2 | |
| SCHEMBL12188521 | 0.76 | CYP1A2 (0.43) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL99535 | 0.74 | HPGD (0.64) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL29656832 | 0.74 | HPGD (0.64) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL6428445 | 0.73 | ALDH1A1 (0.47) | TSHRALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL97298 | 0.73 | TSHR (1.00) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL29904615 | 0.73 | TSHR (1.00) | TSHRALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244953-B1 | ENHANCED LIVINGNESS OF POLYMERIZATION USING SILYLATED OXYANIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-07-18 | — | — | EP | disclosed |
| US-4736003-A | HIGH MOLECULAR WEIGHT ACRYLIC POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-05 | — | — | US | disclosed |
| EP-0244953-A1 | Enhanced livingness of polymerization using silylated oxyanions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-11 | — | — | EP | disclosed |