Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9809004 | 0.87 | ALDH1A1 (0.45) | ALDH1A1DPP4PBRM1KDM4EHSD17B10 | |
| SCHEMBL6430433 | 0.85 | ALDH1A1 (0.63) | ALDH1A1KDM4ETSHRFEN1RAB9A | |
| SCHEMBL7218124 | 0.83 | TSHR (0.51) | ALDH1A1PBRM1HSD17B10TSHRFEN1 | |
| SCHEMBL7219663 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KDM4ETSHRFEN1RAB9A | |
| SCHEMBL7219666 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TSHRFEN1RAB9ALMNA | |
| SCHEMBL6429960 | 0.80 | POLB (0.52) | ALDH1A1KDM4ETSHRRAB9AKMT2A | |
| SCHEMBL6428937 | 0.80 | DOT1L (0.50) | ALDH1A1KDM4EFEN1RAB9AGAA | |
| SCHEMBL27521668 | 0.79 | ALDH1A1 (0.41) | ALDH1A1TSHRFEN1RAB9AKMT2A | |
| SCHEMBL80183 | 0.79 | ALDH1A1 (0.64) | ALDH1A1DPP4PBRM1KDM4EHSD17B10 | |
| SCHEMBL7854774 | 0.79 | PTGS2 (0.58) | RAB9AKMT2ALMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100415750-C | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2008-09-03 | — | — | CN | disclosed |
| CN-1772749-A | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2006-05-17 | — | — | CN | disclosed |
| CN-1239495-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 2006-02-01 | — | — | CN | disclosed |
| US-6924396-B2 | α-haloenamine reagents | PHARMACIA CORPORATION (US) | 2005-08-02 | — | — | US | disclosed |
| CN-1636457-A | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1188419-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 2005-02-09 | — | — | CN | disclosed |
| CN-1188420-C | Fungicides for control of take-all disease of plants | MONSANTO CO (US) | 2005-02-09 | — | — | CN | disclosed |
| EP-1421056-A1 | (ALPHA)-HALOENAMINE REAGENTS | Pharmacia Corporation (US) | 2004-05-26 | — | — | EP | disclosed |
| US-20040092770-A1 | Alpha-haloenamine reagents | PHARMACIA CORPORATION | 2004-05-13 | — | — | US | disclosed |
| US-6677487-B2 | COMBINING A TERTIARY AMIDE WITH A PENTAVALENT PHOSPHOROUS HALIDE IN A SOLVENT TO FORM AN ALPHA - HALOIMINIUM SALT AND CONVERTING THE ALPHA -HALOIMINIUM SALT TO THE ALPHA -HALOENAMINE WITH A BASE | PHARMACIA CORPORATION | 2004-01-13 | — | — | US | disclosed |
| CN-1043835-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 1999-06-30 | — | — | CN | disclosed |
| US-5849723-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5834447-A | THIOPHENE DERIVATIVES | MONSANTO COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-5811411-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5705513-A | HETEROCYCLIC FUNGICIDES WITH PYRIDINE OR FURAN RINGS | MONSANTO COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| US-5693667-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| US-5498630-A | SUBSTITUTED BENZOTHIOPHENECARBOXAMIDES | MONSANTO COMPANY (US) | 1996-03-12 | — | — | US | disclosed |
| CN-1085221-A | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 1994-04-13 | — | — | CN | disclosed |
| WO-1993007751-A1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0538231-A1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092770-A1 | Alpha-haloenamine reagents | HNMT, HDHD5, NISCH | ALDH1A1 373/4885DPP4 3043/4885PBRM1 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.