Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25278252 | 0.81 | POLB (0.51) | MAPK14MAPTGAAALDH1A1KMT2A | |
| SCHEMBL5344718 | 0.81 | RAB9A (0.41) | MAPK14MAPTGAAALDH1A1KMT2A | |
| SCHEMBL3627806 | 0.81 | DCK (0.43) | MAPK14KMT2AMEN1LMNACDK2 | |
| SCHEMBL8303938 | 0.77 | ABCB1 (0.40) | ALDH1A1KMT2AMEN1LMNARAB9A | |
| SCHEMBL7639805 | 0.77 | KMT2A (0.55) | MAPK14MAPTGAAALDH1A1KMT2A | |
| SCHEMBL27622346 | 0.76 | RAB9A (0.37) | MAPTALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL27603628 | 0.75 | PTGS2 (0.36) | MAPK14ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL210468 | 0.72 | RAB9A (0.51) | MAPTKMT2AMEN1LMNARAB9A | |
| SCHEMBL5694141 | 0.71 | DYRK1A (0.47) | MAPTALDH1A1KMT2AMEN1HSD17B10 | |
| SCHEMBL4337861 | 0.71 | NPC1 (0.46) | MAPK14MAPTGAAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193903-B1 | PRODUCTION OF CYTOSINE NUCLEOSIDES | Takeda Chemical Industries, Ltd. (JP) | 1990-06-13 | — | — | EP | disclosed |
| US-4689404-A | Production of cytosine nucleosides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-08-25 | — | — | US | disclosed |
| EP-0193903-A2 | Production of cytosine nucleosides | Takeda Chemical Industries, Ltd. (JP) | 1986-09-10 | — | — | EP | disclosed |