SCHEMBL10349593

SCHEMBL10349593

O=C1C=CN2C(N1)OC1C(O)C(CO)OC12

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PYGM P11217 3/20 0.40
▸ CDA P32320 8/20 0.39
▸ SLC28A1 O00337 1/20 0.39
▸ SLC28A2 O43868 1/20 0.39
▸ SLC29A1 Q99808 1/20 0.39
▸ SLC28A3 Q9HAS3 1/20 0.39
▸ MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31543029 1.00 PYGM (0.40) PYGMCDASLC28A1SLC28A2SLC29A1
SCHEMBL24487839 1.00 PYGM (0.40) PYGMCDASLC28A1SLC28A2SLC29A1
SCHEMBL26553841 0.88 OGA (0.32) —
SCHEMBL21283173 0.77 CDA (0.47) PYGMCDASLC28A1SLC28A2SLC29A1
SCHEMBL18871272 0.75 CDA (0.48) PYGMCDASLC28A1SLC28A2SLC29A1
SCHEMBL26798971 0.74 CDA (0.39) PYGMCDASLC28A1SLC28A2SLC29A1
SCHEMBL23906506 0.72 ALDH1A1 (0.41) PYGMCDASLC28A1SLC28A2SLC29A1
SCHEMBL14510444 0.71 TK2 (0.37) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL23353386 0.71 TK2 (0.37) CDASLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL21283066 0.71 TK2 (0.37) CDASLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120184457-A1 Modulation of miRNA Activity CAMBRIDGE ENTERPRISE LIMITED (GB) 2012-07-19 — — US disclosed
US-20120184457-A1 Modulation of miRNA Activity CAMBRIDGE ENTERPRISE LIMITED (GB) 2012-07-19 — — US disclosed
WO-2011015829-A1 MODULATION OF MIRNA ACTIVITY CAMBRIDGE ENTERPRISE LIMITED (GB) 2011-02-10 — — WO disclosed
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