Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.56 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310332 | 0.90 | REN (0.50) | RENBACE1 | |
| SCHEMBL11039111 | 0.86 | REN (0.55) | RENBACE1 | |
| SCHEMBL8901637 | 0.84 | REN (0.67) | RENBACE1 | |
| SCHEMBL11039196 | 0.83 | REN (0.50) | REN | |
| SCHEMBL5786552 | 0.81 | REN (0.61) | REN | |
| SCHEMBL7309673 | 0.81 | REN (0.51) | RENBACE1 | |
| SCHEMBL7311362 | 0.81 | REN (0.55) | RENBACE1 | |
| SCHEMBL8904372 | 0.81 | REN (0.61) | REN | |
| SCHEMBL7313266 | 0.81 | REN (0.54) | RENBACE1 | |
| SCHEMBL10799861 | 0.80 | REN (0.62) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114993-B1 | RENIN INHIBITORY TRIPEPTIDES | MERCK & CO. INC. (US) | 1990-05-16 | — | — | EP | claimed |