Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039111 | 0.92 | REN (0.55) | REN | |
| SCHEMBL8904372 | 0.89 | REN (0.61) | REN | |
| SCHEMBL10602514 | 0.87 | REN (0.53) | REN | |
| SCHEMBL10598636 | 0.87 | REN (0.53) | REN | |
| SCHEMBL10597992 | 0.84 | REN (0.49) | RENCTSD | |
| SCHEMBL10598784 | 0.84 | REN (0.51) | REN | |
| SCHEMBL10349800 | 0.83 | REN (0.56) | REN | |
| SCHEMBL10598050 | 0.83 | REN (0.52) | RENCTSD | |
| SCHEMBL10598154 | 0.83 | REN (0.52) | REN | |
| SCHEMBL10601854 | 0.81 | REN (0.48) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081783-B1 | RENIN INHIBITORY PEPTIDES HAVING PHE 13 DELETION | MERCK & CO. INC. (US) | 1985-06-19 | — | — | EP | claimed |
| EP-0081783-A1 | Renin inhibitory peptides having Phe 13 deletion | MERCK & CO. INC. (US) | 1983-06-22 | — | — | EP | claimed |
| EP-0081783-B1 | RENIN INHIBITORY PEPTIDES HAVING PHE 13 DELETION | MERCK & CO. INC. (US) | 1985-06-19 | — | — | EP | disclosed |