SCHEMBL10350238

SCHEMBL10350238

O=C(c1ccc(OCC2CO2)cc1)c1ccc(C(=O)c2ccc(OCC3CO3)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
LMNA P02545 3/20 0.60
PKM P14618 2/20 0.60
GAA P10253 2/20 0.60
TDP1 Q9NUW8 1/20 0.59
TP53 P04637 3/20 0.56
TSHR P16473 3/20 0.56
MAPT P10636 3/20 0.56
HPGD P15428 2/20 0.56
HIF1A Q16665 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
CYP1A2 P05177 1/20 0.56
PPARG P37231 1/20 0.56
SMN1; SMN2 Q16637 4/20 0.53
CYP3A4 P08684 1/20 0.53
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
PARP15 Q460N3 3/20 0.47
PARP10 Q53GL7 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12517400 1.00 ALDH1A1 (0.60) ALDH1A1LMNAPKMGAATDP1
SCHEMBL2222829 0.94 PKM (0.54) ALDH1A1LMNAPKMGAATDP1
SCHEMBL1160078 0.94 TDP1 (0.67) ALDH1A1LMNAPKMGAATDP1
SCHEMBL12319180 0.94 TDP1 (0.67) ALDH1A1LMNAPKMGAATDP1
SCHEMBL9774931 0.92 RAB9A (0.57) ALDH1A1LMNAPKMGAATDP1
SCHEMBL2466874 0.92 NPC1 (0.57) ALDH1A1LMNAPKMGAATDP1
SCHEMBL25676308 0.92 PARP15 (0.60) ALDH1A1LMNAPKMGAATDP1
SCHEMBL10736136 0.91 ALDH1A1 (0.51) ALDH1A1LMNAPKMGAATDP1
SCHEMBL10350350 0.91 ALDH1A1 (0.57) ALDH1A1LMNAPKMGAATDP1
SCHEMBL12516194 0.89 GAA (0.51) ALDH1A1LMNAPKMGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312812-A1 EPOXY RESIN THE BOEING COMPANY 2023-10-05 US disclosed
US-20230312812-A1 EPOXY RESIN THE BOEING COMPANY 2023-10-05 US disclosed
US-11718707-B2 Epoxy resin THE BOEING COMPANY (US) 2023-08-08 US disclosed
US-11718707-B2 Epoxy resin THE BOEING COMPANY (US) 2023-08-08 US disclosed
US-20210355269-A1 EPOXY RESIN COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2021-11-18 US disclosed
US-11059937-B2 Epoxy resin THE BOEING COMPANY (US) 2021-07-13 US disclosed
US-20190248953-A1 EPOXY RESIN THE BOEING COMPANY 2019-08-15 US disclosed
WO-2018018070-A1 EPOXY RESIN THE BOEING COMPANY (US) 2018-02-01 WO disclosed
EP-0157740-B1 GLYCIDYLOXYDIKETONES CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed
US-4649181-A Glycidyloxy diketones CIBA-GEIGY CORPORATION (US) 1987-03-10 US disclosed
EP-0157740-A2 Glycidyloxydiketones CIBA-GEIGY AG (CH) 1985-10-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718707-B2 Epoxy resin EPHX2, EPHX1, CBR1 ALDH1A1 636/4885LMNA 954/4885PKM 4597/4885
US-20210355269-A1 EPOXY RESIN EPHX2, EPHX1, CBR1 ALDH1A1 636/4885LMNA 954/4885PKM 4597/4885
US-20190248953-A1 EPOXY RESIN EPHX2, EPHX1, CBR1 ALDH1A1 636/4885LMNA 954/4885PKM 4597/4885
US-11059937-B2 Epoxy resin EPHX2, EPHX1, CBR1 ALDH1A1 636/4885LMNA 954/4885PKM 4597/4885
US-20230312812-A1 EPOXY RESIN EPHX2, EPHX1, CBR1 ALDH1A1 636/4885LMNA 954/4885PKM 4597/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.